Nope, there isn’t. There’s not even any meaning in the separation of Neandertal and us, we’re the same. The Replacement scenario is a body-beautiful/racial superiority model from the 19th century that is going to have to die.
I’m sure you know this information, but it’s possibly new information to others. The reason for Neanderthals extinction, was ineffective internal heat control. Their bodies overheated.
Neanderthal DNA reveals key differences from modern humans.
Analysis of DNA obtained from Neanderthal remains has revealed key differences from modern humans that suggest their bodies produced excess heat.
While in the cold climate of an ice age this would have provided the species with an advantage, as the earth warmed they would have been less able to cope. Ultimately this would have caused their extinction around 24,000 years ago.
Scientists at Newcastle University have put forward the theory after examining a particular form of genetic material which was obtained from the fossilised bones of Neanderthals.
By comparing it with that found in modern humans, they discovered that Neanderthals had key differences in the sections responsible for producing energy in all living cells.
Professor Patrick Chinnery, a neurogeneticist at Newcastle University, believes the differences in this mitochondrial DNA could have caused Neanderthals to be inefficient at producing energy, meaning their cells leaked heat.