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Ebola Surveillance Thread
Free Republic Threads ^ | August 10, 2014 | Legion

Posted on 08/10/2014 12:46:23 AM PDT by Smokin' Joe

I have spent a little time compiling links to threads about the Ebola outbreak in the interest of having all the links in one thread for future reference.

Please add links to new threads and articles of interest as the situation develops.

Thank You all for you participation.


TOPICS: Health/Medicine
KEYWORDS: africa; airborne; cdc; czar; doctor; ebola; ebolaczar; ebolagate; ebolainamerica; ebolaoutbreak; ebolaphonywar; ebolastrains; ebolathread; ebolatransmission; ebolavaccine; ebolaviralload; ebolavirus; emory; epidemic; fluseason; frieden; health; healthcare; hospital; incubation; isolation; jahrling; liberia; nih; obamasfault; obola; outbreak; overpopulation; pandemic; peterjahrling; population; populationcontrol; protocols; publichealth; publicschools; quarantine; quarantined; ronklain; schools; sierraleone; talkradio; terrorism; thomasfrieden; tolerance; travel; travelban; trojanhorse; usarmy
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To: Thud; Smokin' Joe; Black Agnes; ElenaM; PA Engineer; XEHRpa; Cvengr; Shelayne; Tilted Irish Kilt
This is a reply to that “Throw health care worker's lives like logs trying to smother a fire” paper of the CDC that proposed that HCWs need only be protected with the most basic of PPE to deal with Ebola.

Short form — PPE protecting from airborne transmission of Ebola is the minimum necessary to be safe.


The Lancet, Volume 384, Issue 9949, Pages 1181 - 1182, 27 September 2014
doi:10.1016/S0140-6736(14)61346-5Cite or Link Using DOI
Published Online: 10 September 2014

Ebola control measures and inadequate responses

Timothy W Ryschon a

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61346-5/

The title “Is respiratory protection appropriate in the Ebola response?”1 suggests that a critically important hypothesis regarding transmission of Ebola will be discussed. Instead, in their Letter,1 the authors assert that direct contact precautions advocated by the US Centers for Disease Control and Prevention, are sufficient, and argue against more conservative infection control measures.

Despite their insistence that conservative respiratory precautions are not needed, such measures are publicly and repeatedly shown during the repatriation of infected health-care workers to specially equipped medical centres, rather than to any hospital practicing direct contact precautions, reinforcing a serious inconsistency between recommendations and practice.

In the practice of evidence-based medicine, patients are afforded the most conservative interventions until alternatives are substantiated through rigorous scientific methods. When confronted with clinical features and behaviours that defy our expectations, predictions, or understanding, clinical scientists build testable hypotheses around those observations and in the interim protect patients, their caregivers, and contacts with the most conservative precautions.

Our present reality concerns an expanding number of clinicians who were infected while ostensibly observing the direct contact precautions. No evidence has been provided to the contrary. Ebola observers can deduce the epidemiological implications of aerosol transmission described in extant literature, and mentioned although not referenced by Jose M Martin-Moreno and colleagues in their Letter.1 Accordingly, hospital administrators will enact more conservative precautions that either the authors1 or the Centers for Disease Control and Prevention have prescribed.

Scientists should make undiluted risk assessments and serious plans to contain, detect early, and actuate meaningful health-system responses to Ebola infection.

The scientific community must argue for the most conservative infection control responses that make sense in light of the present data. I believe the authors1 and the Centers for Disease Control and Prevention have failed to do that and in so doing, have imperilled individuals unnecessarily.

I declare no competing interests.

Reference

1 Martin-Moreno JM, Llinás G, Martínez Hernández J. Is respiratory protection appropriate in the Ebola response?. Lancet 2014; 384: 856. Full Text | PDF(108KB) | PubMed


Another short form -- the CDC just got called as the PPE "Emperor with no cloths" and nothing is going to get that credibility back for Western HCW or Hospital Administrators.

2,501 posted on 09/26/2014 10:33:58 AM PDT by Dark Wing
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To: Smokin' Joe
Good information at this link:

http://guerrillamerica.com/exercise-stable-phantom/

2,502 posted on 09/26/2014 12:50:13 PM PDT by Oorang (Tyranny thrives where government need not fear the wrath of an armed people - Alex Kozinski)
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To: Dark Wing

If MSF were to leave and then the US Military? It really would be “game over”.

*Shudder*


2,503 posted on 09/26/2014 4:31:26 PM PDT by Shelayne
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To: EternalHope
In my opinion, it is nearly certain that Ebola will infect enough people in the worst hit countries to cause a breakdown in their basic infrastructure.

People will be forced to attempt to flee. Some of them will be infected. Ebola will spread far and wide unless the rest of the world takes horrific steps to isolate the infected areas.

Since the spread is slower than "terrible disease" spread shown in movies (28 Days, WW-Z, Contagion, Planet of the Apes, etc...) it seems people don't think of it as a threat.

2,504 posted on 09/26/2014 7:39:03 PM PDT by Axenolith (Government blows, and that which governs least, blows least...)
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To: Axenolith
It's hard to get an audience to sit through a two to three week incubation period in a Sci-Fi-horror thriller.

Unfortunately, the short attention span theater of the news cycle will probably move on, too. The ensuing complacency works against anyone in harm's way, and had there been less of that in high places, perhaps this outbreak could have been contained months ago.

Those of us used to dealing with change over much greater time spans recognize just how fast this is.

2,505 posted on 09/26/2014 10:50:04 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Axenolith
Since the spread is slower than "terrible disease" spread shown in movies (28 Days, WW-Z, Contagion, Planet of the Apes, etc...) it seems people don't think of it as a threat.

I know. Nothing we do or say can even get their attention. At least for now...

2,506 posted on 09/27/2014 12:25:30 AM PDT by EternalHope (Something wicked this way comes. Be ready.)
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To: Oorang

On the airport list, they missed Minneapolis/St. Paul. Hub airport and the Twin Cities’ area has enclaves of Liberians (25,000+/-) and Somalis (not sure how many, but not so assimilated).


2,507 posted on 09/27/2014 2:40:54 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Smokin' Joe

Oh great. That is just peachy.

Well, it’s not as if that was Patrick Sawyer’s ultimate destination or anything. Oh wait. It was. *smh*


2,508 posted on 09/27/2014 6:40:06 AM PDT by Shelayne
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To: Smokin' Joe
West Africa Ebola death toll passes 3,000 - WHO
2,509 posted on 09/27/2014 8:54:12 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: Smokin' Joe

Yup, I noticed that. I avoid the Minneapolis airport at all costs, too many terrorist connections and now with this...


2,510 posted on 09/27/2014 9:00:42 AM PDT by Oorang (Tyranny thrives where government need not fear the wrath of an armed people - Alex Kozinski)
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To: Smokin' Joe

“West Africa death toll passes 3,000 - WHO”

About all you say about WHO is that their numbers have always been wrong and are getting worse, and their advice is terrible.

Doctors Without Borders has made the human race proud in this.

WHO, and the response of the world in general, has shown human government to be contemptible.

This has been a historic failure of human government in general, but a single individual stands out as more culpable than any other single person: Margaret Chan (the head of WHO).

Firing Margaret Chan would be too good for her.


2,511 posted on 09/27/2014 9:11:51 AM PDT by EternalHope (Something wicked this way comes. Be ready.)
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To: Smokin' Joe
MSF aid worker on the horrors of Ebola

Ebola, there is no more emergency word than Ebola. You know that means now. Ebola means now.

We knew five or six weeks ago, you need a thousands beds, now it's doubled. We need ways for those who cannot help their relatives, we need a way for them to be able to do that. For families to be dying by taking care of their relatives - for me that is so tragic. I don't have other expletives to use.
.......................................................................................................
Figures are really under reported. We know that it's far, far worse than the numbers we have.


This is a long article and MSF is desperate. I figure the infection rate has surpassed 30,000 and the deaths are far greater than reported.
2,512 posted on 09/27/2014 9:41:50 AM PDT by PA Engineer (Liberate America from the Occupation Media.)
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To: PA Engineer
The first good news I've seen on Ebola:
An HIV drug that seems to work on Ebola

The second good news I've seen on Ebola:
Possible anti-viral research breakthrough, including Ebola

Basically, it appears Ebola and HIV share a similar way into the cells they infect. A desperate/inspired doctor in Africa took that basic information and started trying HIV drugs on Ebola patients. The initial read is that it WORKED!!

I found both of these here:
Outstanding Ebola web site thread (Pandemic Flu Information Forum)

2,513 posted on 09/27/2014 11:30:30 AM PDT by EternalHope (Something wicked this way comes. Be ready.)
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To: Smokin' Joe

Anyone following Ebola should check out the links I put in post 2513.

This is the first good news I’ve seen on Ebola. We might already have at least one effective drug.


2,514 posted on 09/27/2014 11:38:58 AM PDT by EternalHope (Something wicked this way comes. Be ready.)
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To: Dark Wing

c 2513.

remember those lamp posts?

A million infected and mostly dead by January maybe but hey, let’s schedule a study for that drug’s effectiveness. It may be dangerous or something with a mortality rate GREATER than ebola. Can’t be too careful! /s

(wanna lay odds they cut off the supply of this drug somehow? (plant fire, accidental contamination, etc))


2,515 posted on 09/27/2014 11:44:07 AM PDT by Black Agnes
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To: EternalHope
From one of the posts at your third link, speaking about the lack of PPE and having to re-use equipment meant to be discarded and burned after 1 use:

"We still do have gaps in the supply, which are quite significant," said Antonio Vigilante, the Deputy Special Representative of the U.N. Secretary-General in Liberia. "Nobody expected that the requirements of protective gear would go in the order of millions." Liberia now requires an estimated 1.3 million protective suits, Vigilante said.

Now imagine the difficulty of keeping up with any major outbreak here...

2,516 posted on 09/27/2014 11:48:40 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: EternalHope

Was just reading The PFIF on this drug. Very interesting and hopeful.


2,517 posted on 09/27/2014 12:13:19 PM PDT by PA Engineer (Liberate America from the Occupation Media.)
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To: EternalHope
Lamivudine

Lamivudine is an analogue of cytidine. It can inhibit both types (1 and 2) of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B. It is phosphorylated to active metabolites that compete for incorporation into viral DNA. They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis. The lack of a 3'-OH group in the incorporated nucleoside analogue prevents the formation of the 5' to 3' phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.

Lamivudine is administered orally, and it is rapidly absorbed with a bio-availability of over 80%. Some research suggests that lamivudine can cross the blood–brain barrier.

2,518 posted on 09/27/2014 12:25:54 PM PDT by PA Engineer (Liberate America from the Occupation Media.)
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To: PA Engineer; EternalHope
PA Engineer:" Very interesting and hopeful."

Quite so !
Also noticed that early medical intervention within the first 5 days of symptoms seems to be the key to overcomming or arresting Ebola.
Frequently, "necessity is the mother of invention" .. and innovation.
The similarity of Zaire , Marburg , and HIV as an invasive virus may have led this doctor to proceed, absent any human trials, and may have lead to possibly control this disease.
It couldn't have come at a better time, considering Ebola's increased spread ,doubleing every three weeks.

2,519 posted on 09/27/2014 8:50:57 PM PDT by Tilted Irish Kilt
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To: Smokin' Joe
Ebola deaths in West Africa 'pass 3,000' - WHO
2,520 posted on 09/27/2014 10:47:28 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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