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Tiny genetic difference splits hunks and wimps
The Daily Telegraph ^ | February 21, 2003 | Roger Highfield

Posted on 02/20/2003 5:52:00 PM PST by MadIvan

Only a tiny genetic difference can separate a macho man from a wimp, says a study published today.

A variation in a single gene may explain why some people can withstand pain - or other physical or emotional stress - better than others, a team from the University of Michigan and the National Institutes of Health reports.

In the journal Science, the team describes how a small variation in the gene encoding an enzyme - catechol-O-methyl transferase, or COMT - made a significant difference in the pain tolerance, and pain-related emotions and feelings, of volunteers.

Genetics may not make all the difference between wimps and Marines, but the finding adds to evidence of variations in individuals' response to pain being mainly due to biological factors affecting the brain.

In the study the pain came from a carefully controlled salt-water injection into the jaw muscles of the volunteers.

By combining genetic testing with molecular brain imaging techniques the researchers could see how well participants' brains controlled pain, and how they felt as a result, depending on their COMT.

The research could help explain how perceptions of pain affect chronic conditions and depressive illness. "Examining and detailing the biochemistry of these processes can then lead to more effective treatments," said Dr Zubieta.


TOPICS: Culture/Society; Extended News; Foreign Affairs; News/Current Events; US: Michigan
KEYWORDS: biology; genes; hunk; wimp
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Call it the French chromosome. Be grateful you lot don't have it. ;)

Regards, Ivan

1 posted on 02/20/2003 5:52:00 PM PST by MadIvan
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To: UofORepublican; kayak; LET LOOSE THE DOGS OF WAR; keats5; Don'tMessWithTexas; Dutchy; ...
Bump!
2 posted on 02/20/2003 5:52:11 PM PST by MadIvan
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To: All

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3 posted on 02/20/2003 5:52:13 PM PST by Bob J
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To: MadIvan
Does this also mean scientists have found a gene for political affiliation?
4 posted on 02/20/2003 5:57:23 PM PST by Boston Capitalist
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To: MadIvan
bump
5 posted on 02/20/2003 6:04:39 PM PST by LiteKeeper
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To: MadIvan
The Gauls were always a tricky bunch, inbred, devious and primitive. Caesar can tell you.
6 posted on 02/20/2003 6:14:00 PM PST by WaterDragon (Playing possum doesn't work against nukes.)
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To: MadIvan
I don't understand this study.

Most women get a cold and they carry on. Most men catch a cold and they whimper about it, and tell everyone they have the 'flu.

You boys don't know pain.
7 posted on 02/20/2003 6:44:38 PM PST by Happygal
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To: Happygal
You boys don't know pain.

True enough, darling. We don't do anything equivalent to childbirth, but then again, no man has ever tried to swallow a watermelon whole and digest it. ;)

Love, Ivan

8 posted on 02/20/2003 6:47:12 PM PST by MadIvan
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To: MadIvan
Eh? Are you suggesting that a man could do it? *L*
9 posted on 02/20/2003 6:53:47 PM PST by Happygal
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To: Happygal
Well I'm not going to try it, darling. ;)

Love, Ivan

10 posted on 02/20/2003 6:54:59 PM PST by MadIvan
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To: Happygal
Most women get a cold and they carry on. Most men catch a cold and they whimper about it, and tell everyone they have the 'flu. But we don't run to the doctors when we are sick.....:)
"Nah. Don't worry about it. No need for the doctor. It's just a case of the flu...."
11 posted on 02/20/2003 7:40:12 PM PST by Dan from Michigan ("Yippee Kai Aye......")
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To: MadIvan
made a significant difference in the pain tolerance, and pain-related emotions and feelings, of volunteers.

Well, my dad has an insane tolerance for pain.(He hammered his thumb with a carpenter hammer and didn't even swear). Mine's not as high as his, but I kept weighlifting right after I first subluxed my shoulder and finished my workout.

I think pain tolerance is mostly in the mind. Guys never want to look weak in front of their dads, sons or other guys. It becomes so habitforming, that the mentality is there at all times. I like the old saying "Walk it off".

12 posted on 02/20/2003 8:02:44 PM PST by Dan from Michigan ("Yippee Kai Aye......")
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To: Dan from Michigan
Talk to me about pain when (a) you defy science and become the first male to birth a baby or ..in the same vein...(b) shit a football.
13 posted on 02/20/2003 8:06:29 PM PST by Happygal
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To: Happygal
I can catch footballs and cause others to fumble em. Close enough? :)...didn't think so.
14 posted on 02/20/2003 8:32:12 PM PST by Dan from Michigan ("Yippee Kai Aye......")
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To: Dan from Michigan
Dan, I love ye toots, but both you and I know you ain't ever gonna lose a football sized being from your body.

So don't even TRY to suggest it.

I don't have kids.
But, even *I* am put off by the pain consequences.

(I will have kids though, I just haven't got me head around it yet!!!)
15 posted on 02/20/2003 8:37:35 PM PST by Happygal
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To: Happygal
...I just haven't got me head around it yet!

Well, there's your problem - that's not how you make babies, HG ;)

16 posted on 02/20/2003 8:42:17 PM PST by general_re (Friends help you move. Real friends help you move bodies.)
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To: general_re
You are not only NAUGHTY, but, damn funny *LOL*

OK, strike one!!..You do know, I will have to stalk you now to get my own back? *LOL*
17 posted on 02/20/2003 8:45:19 PM PST by Happygal
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To: general_re
...I just haven't got me head around it yet!
Well, there's your problem - that's not how you make babies, HG ;)

Of course, the boys don't complain! *LOL*

18 posted on 02/20/2003 8:47:44 PM PST by Happygal
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Comment #19 Removed by Moderator

To: Happygal; MadIvan
Not true, some of us have been fortunate to have kidney stones at an early age. Doctors compare the pain intensity to be about the same as childbirth for women.

Women have labor and give childbirth and the pain subsides. Kidney stones can last for days and painkillers don't help.

I lament that now they have sonic wave machines to dissolve the stones and make the experience shorter.

I have always fantasized that if you could induce the pain of kidney stones on a subject for interrogation he would tell you anything you wanted. It's a wonder that with all of ouir technology we haven't figured out how to do that.

I bet a lot of those Al Q'aida guys would love to willing experimental subjects. Call me a sadist, but I think that would be fun to watch.

I don't care what genes you have, if I were able to induce that kind of pain you'd tell all I wanted to know.

20 posted on 02/20/2003 9:40:58 PM PST by Cacique (Censored by Admin Moderator)
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