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Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus...(Re-post)
Axios ^ | March 18 ,2020 | Caitlin Owens

Posted on 03/18/2020 11:54:35 AM PDT by yoe

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To: yoe

I sold my Gilead today. Barely made anything. But when it drops 20% tommorow, I may pick it up again at a better price than I had it for.


61 posted on 03/18/2020 1:37:14 PM PDT by Old Yeller (Auto-correct has become my worst enema.)
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To: Truth29

I didnt have quinine, so I got equine. Gotta feed him hay twice a day now.


62 posted on 03/18/2020 1:38:46 PM PDT by Old Yeller (Auto-correct has become my worst enema.)
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To: griffin

“I think I found what my ex-wife was on all the time we were married then!”

Does just everything you can think of to a body!


63 posted on 03/18/2020 1:39:37 PM PDT by LouieFisk
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To: VanShuyten; Kid Shelleen
John Hopkins guy this morning on the radio said chloroquine and azithromycin, a very common antibiotic, seem to work very well.

Sounds promising.When it comes to "cutting edge" medicine schools like Hopkins (and a few others) are the ones to trust.I,for one,don't trust a single word about the virus (or anything else) uttered by the Chinese...for obvious reasons.

64 posted on 03/18/2020 1:55:51 PM PDT by Gay State Conservative (The Rats Can't Get Over The Fact That They Lost A Rigged Election)
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To: LouieFisk

“I read the side effects Good God it makes coronavirus look like a walk in the park”


The big one for chloroquine is widening of the heart’s QT interval(worse than Z-Pak and some other antibiotics) so you get pushed into V-Tach and/or heart attack. Combine that with Covid19 sometimes inflammation of the heart muscle(myocarditis) and....well, yeah. STRICT supervision required to try to go that route.


65 posted on 03/18/2020 2:00:01 PM PDT by JCL3 (As Richard Feynman might have said, this is reality taking precedence over public relations.)
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To: JCL3

“The big one for chloroquine is widening of the heart’s QT interval(worse than Z-Pak and some other antibiotics) so you get pushed into V-Tach and/or heart attack. Combine that with Covid19 sometimes inflammation of the heart muscle(myocarditis) and....well, yeah. STRICT supervision required to try to go that route.”

Yup, sounds like it could be risky for those with existing cardio-vascular conditions.


66 posted on 03/18/2020 2:11:06 PM PDT by LouieFisk
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To: Sooth2222

Your point on Kaletra (lopinavir/ritonavir)is well taken. Used alone or in combination with chloroquine or tamiflu, there have been 3 reports from Asia (Thailand, S. Korea, and recently from Singapore in the NEJM) that Kaletra has efficacy vs. the Wuhan virus. Additionally, the extensive clinical experience and the FDA licensing of Kaletra suggests that it has acceptable levels of toxicity. So it is puzzling that the Feds (Dr. Fauci et al) are focused on developing remdesivir (a Gilead compound, which has not yet been approved by the FDA and therefore not fully tested for toxicity)for the Wuhan virus. Gilead, of course, was well known a few years back for charging about $80,000 for enough of their anti-viral for Hepatitis C infections to treat ONE patient....

The one clue to explain this may be that the Abbvie (Kaletra’s manufacturer) website indicates that they do not anticipate any interruption in the supply of Kaletra for their customer base—i.e., the HIV patient community, (I suspect due to contractual obligations). So this suggests to me that there may not be a lot of additional Kaletra available in the US to treat Wuhan virus patients.

In the current environment, most of the chemical powders needed to make the pills sold in US pharmacies are produced in southern China. These chemical powders can be made into pills in China, or shipped elsewhere in the world for processing. It would not surprise me if any extra capacity the primary producers in China have to make the agents used in Kaletra is now being sold on the open market, to the highest bidder, by those manufacturers. As such, we should not expect the ramped-up supplies all to make it to the US market. In fact, it would be surprising if they did.

Thus, I think the Feds may be looking to Gilead to fill the gap with their experimental compound to treat the Wuhan virus victims. The good news is that it has been reported to work, at least on a few patients. And in a pinch, treating clinicians might give Wuhan patients “off label” cloroquine or hydroxychloroquine, as it has been suggested to work by reports from China...


67 posted on 03/18/2020 2:41:43 PM PDT by Carborundum
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To: Truthoverpower

“ A properly prepared colloid of silver ...”

HA!HA!HA!HA!HA!HA!HA!HA! HA!HA!HA!HA!HA!HA!HA!HA!
HA!HA!HA!HA!HA!HA!HA!HA! HA!HA!HA!HA!HA!HA!HA!HA!


68 posted on 03/18/2020 2:41:49 PM PDT by VanShuyten ("...that all the donkeys were dead. I know nothing as to the fate of the less valuable animals.")
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To: FormerFRLurker

Our best bet is to develop a vaccine against the novel coronavirus and that’s not likely to happen this year, according to my MIL’s doctor friend.


Best bet long-term but if something else helps now you do it now.


69 posted on 03/18/2020 3:23:16 PM PDT by boycott
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To: boycott

We’ll have to fight this thing on multiple fronts.


70 posted on 03/18/2020 3:25:12 PM PDT by dfwgator (Endut! Hoch Hech!)
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To: dfwgator

We’ll have to fight this thing on multiple fronts.


Absolutely.


71 posted on 03/18/2020 3:30:05 PM PDT by boycott
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To: Romulus

“No, you can’t come over.”

Party pooper! ;-)


72 posted on 03/18/2020 6:08:19 PM PDT by Pining_4_TX (The Nazis were socialists, and all socialists turn into Nazis.)
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To: NativeSon

You’re all set, then!


73 posted on 03/18/2020 6:08:46 PM PDT by Pining_4_TX (The Nazis were socialists, and all socialists turn into Nazis.)
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To: LouieFisk

“I read the side effects Good God it makes coronavirus look like a walk in the park”

Yeah, but at least I didn’t see uncontrolled oily anal discharge listed as one of the side effects.


74 posted on 03/18/2020 6:27:41 PM PDT by willk (A bias news media is not a free press.)
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To: raisetheroof

Do not taunt Happy Fun Ball!


75 posted on 03/18/2020 6:29:04 PM PDT by dfwgator (Endut! Hoch Hech!)
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To: willk

“Yeah, but at least I didn’t see uncontrolled oily anal discharge listed as one of the side effects.”

Yeah, well, it can’t have all the fun.


76 posted on 03/18/2020 8:20:09 PM PDT by LouieFisk
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