Genghis Khan made a credible effort, but even he failed.
It could be done, but the first world nations which have the tech, do not have the will.
As Grace G said upthread, it would be necessary to kill every last one of them.
Never going to happen.
Alexander the Great “won”, sort of. He defeated their armies, then exterminated every village that supported the fighters. After five years or so Oxyartes, the main “king” opposing him agreed to swear allegience in exchange for continued rule, and Alexander married his daughter Roxana to seal the deal.