What does this mean?
It means that any Sunni Moslem can be turned to killing in the name of Islam, inspired by the re-creation of the Caliphate. This means that any Sunni Moslem -- even, probably especially a new convert (can be a blue-eyed blonde convert or a black or a Chinese or a native American) will kill in the name of the IS.
There is no way to guard against this philosophy by profiling -- while you can profile an Arab, the IS may prompt a Swedish convert or a Japanese or Chinese or Nigerian to do the deed. The all-American looking boy next to you may turn out to be the perpetrator next time
Islamic State has been encouraging “lone wolf” attacks for some time. So they are responsible.