Trump will get the Dan Quayle, Sarah Palin, Newt Gingrich treatment. They will attempt to drive his negatives so high that only Trumps' hard core supporters will vote for him. This strategy pretty much always works with enough effort. And of course supporters of GOPe candidates (the entire field other than Trump) will cheer form the side lines hoping to inherit voters that will no longer vote Trump. However the not trump candidates that sat on the side lines cheering the smear campaign to trash Trump will never get the hard core supporters of Trump and consequently lose in the general election. Right now Trump has a firm 25% of GOP voters and likely a firm 25% of independents. That is a lot of voters to royally piss off.
But the Uniparty does not care they will be perfectly happy with anyone other then Trump. Hillary, Cruz, Rubio, Jeb are all acceptable to the globalist ruling class. Only Trump threatened their gravy train. Only Trump is not owned by billionaire donors, Chamber of Commence, Club for Growth, and the Wall St bankers. The rest not so much.
That is why we should ‘try’ to keep Reagans 11 commandment in mind.
Off topic, lets not get too happy with Trump. Add up Bush, Kasich, Rubio, Christie and Fiorina and GOPe still is quite formidable.