I lived in central MS in my 20’s for 2 years in a row with no a/c in my apartment, car, or workplace. I survived. But I had grown up w/o a/c in my school, my parents car or my grandparents house and mother who was super duper frugal with a/c at our house (thermostat set on 80 in the summer). But there are no ‘sea breezes’ in central Mississippi either...
When I lived in Ohio I had an apartment around the corner from some type of freight terminal where they unloaded pigs. Sometimes on a hot summer day while I was at work the air would kick on, and suck all of that pig-smell straight into my little 1BR flat.
A very rude surprise for me when I got home.