About the only issue the Republicans have is the decline in income of the middle class of ~ 8%, where the perceived solution is bolstering small business. I think Hilary as former Secretary of State neutralizes foreign policy issues.
How this narrative can strip significant Black-Asian-Latino-Jew voters, I don't know. Some yes, enough, probably not.
Add to the demographic factors, Obama beat Romney 55% to 45% with women voters who were 53% of the total electoral. Romney won among men 52% to 45%.
Clinton conceiveably could do better with women than Obama.