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Permanent brain damage:
Research has shown that IQ is a strong determinant of a persons access to a college education, their lifelong total income, their access to a good job, their performance on the job, their tendency to develop heart disease, Alzheimers disease, and even early death, she said.
Individuals who lose eight IQ points in their teens and 20s may be disadvantaged, relative to their same-age peers, in most of the important aspects of life and for years to come.
http://www.telegraph.co.uk/health/healthnews/9426205/Cannabis-smoking-permanently-lowers-IQ.html
http://www.livescience.com/22711-smoking-marijuana-lowers-iq.html
Depression, schizophrenia:
http://learnaboutmarijuanawa.org/factsheets/mentalhealth.htm
Lungs
Marijuana Smokers Face Rapid Lung Destruction -- As Much As 20 Years Ahead Of Tobacco Smokers
http://www.sciencedaily.com/releases/2008/01/080123104017.htm