They want to destroy any non-Islamic nation, for starters. But more than that it is intolerable to them that any non-Muslim should be successful.
The overwhelming fact that Western Civilization and Judeo-Christian religious belief system, together has resulted in a wildly successful Europe and North America, all the while the Islamic part of the world has been unable to keep up technologically and materially, generally infuriates Muslims. So they want to destroy us.
The Israeli-Arab conflict has nothing to do with their angst.
Muslims are horrified at the comparisons between their lack of scientific advances compared to the rest of the world.
Absolutely right, but we mustn’t say this out loud. In fact, Obama has sent the head of NASA to the Middle East to explain that everything the West has accomplished in the world of science and space tech, not to mention computers, tv, medicines, and anything else of practical use was really invented by Arabs. With a deep bow, of course.