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Potential Alzheimer's, Parkinson's Cure Found In Century-old Drug
ScienceDaily ^ | Aug. 18, 2008

Posted on 07/09/2009 8:02:25 AM PDT by MetaThought

ScienceDaily (Aug. 18, 2008) — A new study conducted by researchers at Children's Hospital & Research Center Oakland shows that a century-old drug, methylene blue, may be able to slow or even cure Alzheimer's and Parkinson's disease. Used at a very low concentration – about the equivalent of a few raindrops in four Olympic-sized swimming pools of water – the drug slows cellular aging and enhances mitochondrial function, potentially allowing those with the diseases to live longer, healthier lives.

A paper on the methylene blue study, conducted by Hani Atamna, PhD, and a his team at Children's, was published in the March 2008 issue of the Federation of American Societies for Experimental Biology (FASEB) Journal. Dr. Atamna's research found that methylene blue can prevent or slow the decline of mitochondrial function, specifically an important enzyme called complex IV. Because mitochondria are the principal suppliers of energy to all animal and human cells, their healthy function is critical.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: News/Current Events
KEYWORDS: alzheimers; methyleneblue; parkinsons; parkinsonsdisease
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To: MetaThought

Read later.


61 posted on 07/09/2009 9:07:19 AM PDT by EagleMamaMT ("Uncle Sugar: Handle it at the border or Uncle Winchester will handle it at the porch." Squantos)
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To: spectre

After you discover it worked once. You give high doses to lab rats and keep reducing the dose until it quits killing them. Then you give it to infected rats in ever smaller doses until it quits curing them. The effective dose is somewhere in that range between doesn’t work and kills you.
Step two is to extrapolate the quantity to humans and work from the minimum effective dose up to the point it turns the whites of your eyes blue.
However, this is all academic because with the Obama Health Plan there won’t be any research that matters.


62 posted on 07/09/2009 9:09:07 AM PDT by Steamburg ( Your wallet speaks the only language most politicians understand.)
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To: the long march

Just the mention of the name gave me flashbacks of two weeks in a piss-smelling, yellowing wall room in an African country I will not name.

Fever. Chills. Fever. Chills. Sh!tting out my entire intestinal system. Fever. Chills.

Probably one of the lowest points of my life.


63 posted on 07/09/2009 9:09:51 AM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem.)
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To: MetaThought

Bump


64 posted on 07/09/2009 9:10:17 AM PDT by painter (No wonder democrats don't mind taxes.THEY DON'T PAY THEM !)
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To: Jewbacca

And malaria is so preventable and so treatable. Anyway glad you survived to tell the story


65 posted on 07/09/2009 9:12:32 AM PDT by the long march
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To: RinaseaofDs
Some of that happened in Canada when it was showed that Capscacin was shown to reduce swelling in islet cells in the pancreas, curing diabetes type one in rats. That news, and both researchers, left the face of the earth somehow.

The problem in the case of diabetes research is that rodent results are notoriously unreliable predictors of how humans will respond to the same treatment. They've "cured" diabetes in mice several different ways, bot those treatments have not been successful on humans.

Moreover, just the fact that you haven't seen it in the news doesn't mean researchers aren't looking at it. I would suspect that one of the biggest initial barriers to even contemplating a capscacin treatment is how to deliver it to the pancreas in the first place: that's a huge engineering problem in and of itself. And then, once the engineering is done, there's the expense and difficulty of human testing. It takes years to go from mice to humans....

66 posted on 07/09/2009 9:19:44 AM PDT by r9etb
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To: the long march

interesting... thanks. I’ll pass it along to him.


67 posted on 07/09/2009 9:37:17 AM PDT by Safrguns
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To: MetaThought

So it will be available to the public in about 100 years?


68 posted on 07/09/2009 9:38:36 AM PDT by GSWarrior
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To: MetaThought

Who’d thought it? The antidote for cyanide poisoning and the primary stain of the Graham Stain for bacteria is the cure for Alzheimer’s.


69 posted on 07/09/2009 10:20:17 AM PDT by vetvetdoug
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To: Bellflower

PING


70 posted on 07/09/2009 10:53:34 AM PDT by sjeann
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To: null and void; DJ MacWoW

Cowdini is way too clever for a cow.
Waaaay too clever.


71 posted on 07/09/2009 11:09:17 AM PDT by Darksheare (Tar is cheap, and feathers are plentiful.)
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To: GSWarrior

You can go out and buy it today, if you really want to.

And yes unfortunately clinical trials take time.


72 posted on 07/09/2009 11:13:30 AM PDT by MetaThought
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To: Tennessee_Bob

Yeah, but absolutely hilarious when you’re dealing with a bunch of MIT freshmen who are not generally social lions in high school and who may have never gotten drunk in their lives before.


73 posted on 07/09/2009 11:23:14 AM PDT by RonF
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To: Steamburg

It’s easier on the rats if you work up from the small doses...


74 posted on 07/09/2009 11:24:26 AM PDT by null and void (We are now in day 170 of our national holiday from reality.)
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To: Jewbacca

So, I take it you’ve never been married, nu?


75 posted on 07/09/2009 11:26:05 AM PDT by null and void (We are now in day 170 of our national holiday from reality.)
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To: Darksheare

She’s watching you.

And taking notes.

For Gary Larson...


76 posted on 07/09/2009 11:28:29 AM PDT by null and void (We are now in day 170 of our national holiday from reality.)
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To: Jewbacca

But do you still look like a Fremen ? ;-)


77 posted on 07/09/2009 11:30:00 AM PDT by fieldmarshaldj (~"This is what happens when you find a stranger in the Alps !"~~)
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To: MetaThought
My father was afflicted with Parkinsons. I guess that puts me more at risk although I understand it is not necessarily hereditary.
78 posted on 07/09/2009 11:32:22 AM PDT by GSWarrior
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To: null and void
Probably some alien supercow that is in hiding here to observe us.

Now what's this Alzheimer stuff..?
Turns eyes blue and pee green?
Hmmm... might as well mess the cow up a bit.
Make it look obviously alien.
Maybe then it won't keep coming out of the enclosure to stop me in the road.

79 posted on 07/09/2009 11:32:47 AM PDT by Darksheare (Tar is cheap, and feathers are plentiful.)
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To: MetaThought

I hope this is true. God, do we need it.


80 posted on 07/09/2009 11:34:42 AM PDT by WashingtonSource
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