A physician and a Wapo staff writer. Yes, they should have a nice combined salary.
From the article:
We pay taxes in the highest bracket.
For 2006 married filing jointly, that is at least $336,550 of taxable income. If the house was "only" $459,275, they should be able to pay it pretty easily. Their interest only payments at 5.125% (until they adjust upwards) would be less than $2,000 per month.
If they are having any problems at all it is because they can't handle money.