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To: Prince Charles
Yes, I think AZT is a protease inhibitor.

No. It is a polymerase inhibitor with slightly higher spcificity for reverse transcriptase, an RNA polymerase used by retroviruses.

Sars is an RNA virus but is not a retrovirus.

11 posted on 05/13/2003 12:00:22 PM PDT by tallhappy
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To: tallhappy
Okay thanks.
12 posted on 05/13/2003 12:03:41 PM PDT by Prince Charles
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To: tallhappy
In AIDS a protease inhibitor acts by cutting an enzymatic link in the reproduction of the HIV virus.

I have read that there are fears from some in the medical/scientific community that PI could cause dangerous mutations. (as if it isn't dangerous enough). My understanding is that people taking the cocktails early on kill some of the virus but not all. Those surviving virus live on to reproduce mutated forms

Also, they are toxic. Some have strange effects on people's weight. They call it "protease paunch". Paunches, buffalo humps in the neck, puffy cheeks among other weird things.

13 posted on 05/13/2003 2:25:36 PM PDT by riri
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