Posted on 12/22/2022 5:42:56 AM PST by FarCenter
Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction1,2,3 during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with some patients experiencing prolonged symptoms, termed post-acute sequelae of SARS-CoV-2 (refs. 4,5). However, the burden of infection outside the respiratory tract and time to viral clearance are not well characterized, particularly in the brain3,6,7,8,9,10,11,12,13,14. Here we carried out complete autopsies on 44 patients who died with COVID-19, with extensive sampling of the central nervous system in 11 of these patients, to map and quantify the distribution, replication and cell-type specificity of SARS-CoV-2 across the human body, including the brain, from acute infection to more than seven months following symptom onset. We show that SARS-CoV-2 is widely distributed, predominantly among patients who died with severe COVID-19, and that virus replication is present in multiple respiratory and non-respiratory tissues, including the brain, early in infection. Further, we detected persistent SARS-CoV-2 RNA in multiple anatomic sites, including throughout the brain, as late as 230 days following symptom onset in one case. Despite extensive distribution of SARS-CoV-2 RNA throughout the body, we observed little evidence of inflammation or direct viral cytopathology outside the respiratory tract. Our data indicate that in some patients SARS-CoV-2 can cause systemic infection and persist in the body for months.
(Excerpt) Read more at nature.com ...
They did this study only on unvaxxed people
Now they should repeat on vaxxed esp “ died suddenly” a year or more after vaxx
So the Chinese are efficient
And inscrutable.
My own longstanding hypothesis is that the virus exhibits a latency, but though I haven’t read the linked paper (yet) it’s curious that the word ‘latent’ doesn’t appear once.
It’s hard to believe that the researchers wouldn’t consider it during their research and at least include such consideration in their paper, as well as their results.
As a result, until I’ve read the whole thing the paper smacks suspiciously negligent in omission.
A rare instance of the Feds getting their money’s worth for something... gain-of-function R&D.
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Died with Covid… then.. almost 240 days later, still detected. Sequelea will do what it was designed to do.
This is non news in immunology. I am still laughing though.. died of covid, but nearly 140 days later… I just can’t buy that one. Either the tissue was preserved, then tested up to 240 days later.. which negates their statement. Or they really looked at unpreserved tissue almost 240 days later.
I would not want to cut that old tissue with the microtome. Ewwww.
The analysis was done on fresh tissue of people who had severe Covid, survived up to 240 days and then died. Most likely they never really recovered and had symptoms of “long Covid”.
A relative had severe Covid, never really recovered and died more than a year later after being in and out of hospitals, nursing homes and a hospice.
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