Posted on 12/14/2021 4:57:01 AM PST by null and void
Thank you for the info.
“You should stop. First generation antihistamine use is strongly correlated with development of dementia later on.”
What does “later on” mean? I’m already 80 yrs old.
CLINICAL MISINFORMATION: THE CASE OF BENADRYL CAUSING DEMENTIA
May 22, 2013
In July 2010, Campbell, Boustani and colleagues published the results of a 6-year longitudinal observational study on the cognitive function of 1,600 African Americans over the age of 70 and the association with medications with anticholinergic side effects.[2] The study enrolled individuals who were cognitively normal at baseline. The participants were then reevaluated at least once for cognitive decline at 3 and 6 years of follow-up. Data on patient’s medications with anticholinergic side effects were based on participants reported medication use as well as over-the-counter and prescription bottles belonging to the patients.[3]
The results of the Campbell study are as follows: of the study participants, 179 of 1,652 (11%) were deemed to be exposed to “definite” anticholinergic medications. In that group, the odds ratio for “cognitive impairment” was 1.43, which was not statistically significant to a p-value of 0.05. When corrected based on the number of drugs with anticholinergic effects an individual was taking, the odds ratio for cognitive impairment was 1.46 with a p value of .0181. However, overall the authors conclude that their data did not support the hypothesis that the use of anticholinergic medications increased the risk of alzheimer’s dementia and that the results simply “suggested” a link between this class of medications and “mild cognitive impairment”.[2]
After forty-five minutes of researching and using information databases that are only accessible to me via my medical school library, I had found that the information my friend’s original fear was based on was at best inconclusive. A study with internal validity only to African-Americans over the age of 70 which “suggested” that anticholinergic use may be linked to mild cognitive impairment had, through the evolution of information, been applied to the general population and concluded that medications like Benadryl caused memory loss.
https://www.clinicalcorrelations.org/2013/05/22/clinical-misinformation-the-case-of-benadryl-causing-dementia/
It is generally accepted in in medicine that anticholinergic use does result in later symptomology (causal). I used to keep a list of references in my bookmarks but would have to re-search those now. There were multiple studies, not RCTs, of course, but convincing longitudinal studies. I myself was taken off an Rx drug for this reason.
Believe what you want.
null and void :" Tomorrow's headline: "Lactoferrin Banned By Fauci"
"Hope I'm wrong..."
“Like diphenhydramine, lactoferrin is available without a prescription. Ostrov thought about pairing it with diphenhydramine and ran with the idea.
In lab tests on human and monkey cells, the combination was particularly potent:
Individually, the two compounds each inhibited SARS-CoV-2 virus replication by about 30%.
Together, they reduced virus replication by 99%. “ (Emphasis mine)
What are the two compounds which reduced viral replication :
diphenhydramine = benedryl (sold as sleep aid, allergy medication)
lactoferrin = milk (bovine and/or human)… which probably explains why children may be less affected
Next week a drug company will apply for a patent on a drug that combines the two.🙄
In vitro. Where is the study?
Prozac does, and in vivo.
This was done in petri dishes.
When my brother and sister in-law were sick, I was exposed to Delta. I was taking Benadryl and making myself a Mocha latte daily for breakfast and lunch. I was also taking the daily C, Zine, B, and D.
I got mild symptoms but never got real sick. They might be on to something here.
See tagline.
“Believe what you want.”
I will believe what makes sense after research on the subject.
Send me some info if you have it.
3 antihistamines are being looked at because they are also ace2 inhibitors
https://sbgg.org.br/wp-content/uploads/2021/01/6-ANTI-HISTAMIN.pdf
azelastine
Diphenhydramine
Hydroxyzine
Someone upstairs is really looking out for me.
In January 2020 while in Thailand and got Covid real bad, I took lots of Benadryl and Hydroxychloroquine... This was prior to anyone knowing what worked.
I always take Benadryl when I get a chest cough to stop the sinus drain and the Hydroxychloroquine was a prophylactic for malaria as I spent a week traveling by boat on the Mekong River.
The vax didn’t get as far as petri dishes before being forced on the public.
I had found a detailed Chinese study on lactoferrin in various stages of maternal lactation in various ethnicities and assorted regions. Then my Chromebook erased all my tabs and that page, and I only found this aummary.
https://pubmed.ncbi.nlm.nih.gov/30189612/
https://www.researchgate.net/publication/326341264_Lactoferrin_level_in_breast_milk_a_study_of_248_samples_from_eight_regions_in_China
It seems the earliest milk has the highest lactoferrin content and it lowers over time and stabilizes after the third month from birth. Now I will find some data on animal milk which is far lower in lactoferritin than human milk. I wonder if any studies have been done on the degree of illness in breast fed babies versus cows milk or factory formulas
https://viva.org.uk/health/a-comparison-between-human-milk-and-cows-milk/ While this study does not refer specifically to ferritin, there are some interesting comments under IRON. The chart comparing vitamin and mineral content of cow and human milk is also of interest.
Human milk is rich in lactoferrin, with a concentration around 1–2 mg/mL [7–9], whereas lactoferrin concentration in ruminant milk is 10–100 times lower than in human milk (in the range of 0.02–0.2 mg/mL) [10, 11].Mar 19, 2014
This was the best (only?) article I found comparing lactoferrin in humans, goats, and cows.
https://www.researchgate.net/publication/260149810_Characterization_of_goat_milk_lactoferrin_N-glycans_and_comparison_with_the_N-glycomes_of_human_and_bovine_milk
Annual vaccines, the money machine for big pharma. I wonder if failure to find vaccine for AIDS was becaue it would have been a multi-year vaccine like mumps, tetanus, etc., rather than annual. Current AIDS treatment is multiple drugs given daily for life. Why would big pharma ever want an AIDS vaccine?
Is that why Fauci failed to promote one.
Plenty of lactoferrin supplements on Amazon. Already got plenty Benadryl.
bkmk
I had read hay fed cows have more lactoferrin in the milk than grass fed cows. Don’t ask me why. I try and drink organic grass fed cow milk. Same idea as with eggs, etc. I need to find a local farm for eggs.
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