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To: RaceBannon

They’re talking about false positives.

If a test had a 50% false positive rate, I’d consider it worthless, and I think most others would to. For example, you could then test a population where absolutely no one had, or ever had, the virus and conclude that 50% had been infected and you were close to herd immunity.

How can the CDC say this?

Manufacturers have been claiming 95 to 99% accuracy. I’d say its extremely important to have some accuracy here.


3 posted on 05/28/2020 4:24:11 AM PDT by Pearls Before Swine
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To: Pearls Before Swine

How do you know that the concept of “herd immunity” exists for this virus?


4 posted on 05/28/2020 4:25:52 AM PDT by Jim Noble (Think like youÂ’re right, listen like youÂ’re wrong)
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To: Pearls Before Swine

It is important to for the WHO and CDC to squash hopes of those who test positive for antibodies. If this test is valid, then you don’t need a vaccine. Trillions at stake here for the ghouls imprisoning the serfs until the vaccine (heavenly choir singing) that everyone must take and must be certified after elections.


10 posted on 05/28/2020 4:35:55 AM PDT by epluribus_2 (He, had the best mom - ever.)
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To: Pearls Before Swine

Is the CDC playing politics again?


12 posted on 05/28/2020 4:38:07 AM PDT by xzins (Retired US Army chaplain. Support our troops by praying for their victory.)
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To: Pearls Before Swine

I think CDC is saying that the rate of false positives can be high relative to the number of positives in a large sample of tests. For example, if 1% of a population has the virus, but the test has a false positive rate of 1%, then 2% of the people tested will get a positive result - those actually positive and the false positives. In this case 50% of the positives are false.
But if 20% of the population actually has the virus, an additional 1% false positive is only 1/21 of the total number of positives (less than 5% of the positives are false positives)


16 posted on 05/28/2020 4:44:03 AM PDT by brookwood (Obama said you could keep your plan - Sanders says higher taxes will improve the weather)
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To: Pearls Before Swine

What they are saying is that in populations with low infection rates a large percentage of positive tests will be false positives.
Of course that is true. If a population has a true infection rate of 0%, then the false positives will constitute 100% of the reported positives.
If a population has a 1% true infection rate and the test has a 1% false positive, then the testing will report about 2% positives and the false positives will constitute about 1/2 of the reported positives.


25 posted on 05/28/2020 5:41:08 AM PDT by conejo99
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To: Pearls Before Swine

If the accuracy rate is 95-99% and the actual incidence rate is 1-5%, it’s going to falsely identify cases at about the same rate it “accurately” identifies cases.


38 posted on 05/28/2020 8:08:56 AM PDT by Brellium ("Thou shalt not shilly shally!" Aron Nimzowitsch)
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To: Pearls Before Swine

it doesn’t mean the test has a 50% false positive rate.

If the test yields a false positive 5% of the time, in a population with 5% actual frequency, then it would mean that half of the folks testing positive wouldn’t actually have the disease. If the actual frequency were 2%, then the false positives would be over 70% of those getting positive results.

The first papers showing high detection rates without false positives were done under specific conditions with fewer than 10 examples.

Even if the tests themselves were perfectly accurate, there are always potential issues with executing the tests which could result in false positives, such as environmental contamination.


58 posted on 05/30/2020 2:24:07 PM PDT by lepton ("It is useless to attempt to reason a man out of a thing he was never reasoned into"--Jonathan Swift)
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To: Pearls Before Swine

In the real world of In Vitro Diagnostic Kits and other text kits, a 50% false positive rate would have a rather difficult time being approved by the FDA.


62 posted on 05/30/2020 6:45:19 PM PDT by Toirdhealbheach Beucail (Am fear nach gheibh na h-airm 'n am na sith, cha bith iad aige 'nam a chogaidh)
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