Posted on 03/30/2020 8:18:54 AM PDT by Tennessean4Bush
The cloak of being an off-patent drug which Pharma can't price at $500/tablet.
No doubt Pharma is intensely trying to come up with patentable versions which have some activity against SARS-CoV-2 in time to crowd out the off-patent version and get some of the pandemic pie.
That’s a huge promise - cutting the mean length of stay in the ICU from 12 to 6 days, and reducing the severity overall will be an enormous time, money, and life-saver.
The average length of time in the ICU is 12 days for COVID-19. The average length of time in the ICU for a patient who ends up dying due to COVID-19 is 28 days. So, yes, he is saying that if he gets a patient so far gone that he can't make it 3 days on this treatment (e.g. on the 24th day of stay in ICU), he is not going to count him in his efficacy cohort as having undergone the treatment. That's perfectly fine so long if that is clear up-front, which it is.
Further, this perfectly coincides with his samples he has shown in his previous studies where the hydroxychloroquine and azythromycin does not really begin to do all that better in reducing the virus markers compared to the control group until day 3 where it really begins to take effect.
I don't mind that you post a caveat. What bugs me is that you compose it like he was trying to hide something when he posted it in plain view. And to top it off, you act like you are in the know when you really don't know the basic facts.
Sorry I got a little carried away. I’m sure we both hope for the same thing - a better prognosis.
calm down he just forgot the /s or j/k
That's worth considering. I haven't found anywhere that this was stated either way, but now I know to look out for it.He's not playing games as far as I can tell. He is stating up front his tracking parameters and showing both scenarios right next to each other. How is showing the two data cohorts next to each other "playing games"?
The average length of time in the ICU is 12 days for COVID-19. The average length of time in the ICU for a patient who ends up dying due to COVID-19 is 28 days. So, yes, he is saying that if he gets a patient so far gone that he can't make it 3 days on this treatment (e.g. on the 24th day of stay in ICU), he is not going to count him in his efficacy cohort as having undergone the treatment. That's perfectly fine and it's a common practice by people doing studies so long if that is clear up-front, which it is.
Further, this perfectly coincides with his samples he has shown in his previous studies where the hydroxychloroquine and azythromycin combination does not really begin to do all that better in reducing the virus markers compared to the control group until day 3 where it really begins to take effect.
HCQ and Azithromycin and zinc supplementation does not kill of the circulating virus, the immune system does that. By reducing the viral load the patient’s immune system efficiency is exponentially increased and they spread less virus.
Zinc is an essential part in the reduction of viral load: start at about 1 minute 40 seconds: https://www.youtube.com/watch?v=U7F1cnWup9M&feature
a vaccine is still going to be needed to help make herd immunity though cause this will likely end up endemic like flu
Where's this story: "guy came in with shortness of breath, tested positive for COVID, was given hydroxychloroquine + azithro, he got worse, he died? Even just "he got worse, ended up on a ventilator". I haven't seen it.And you know if that story did exist, it would be published and touted far-and-wide.
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