Two picks is minimum.
RBG, Breyer, and Thomas are likely to all be replaced within the next three years. Alito might also be on the list (he’s 69 currently).
Very likely Trump gets to appoint 4 more Justices to the Supreme Court. If Justice Alito and Justice Thomas both decide they want to avoid a potential RBG situation and step down gracefully, it could be a total of 5 more Trump Supreme Court picks.
This explains impeachment and why the Left is freaking out
The Democrats have a very good shot taking the Senate in 2022