That wouldn't work if I was designing the drone. I'm pretty sure a lot of other people know how to harden a drone against microwave energy. You would think the Cartels could afford to hire people who know what they are doing.
The field is evolving pretty quickly, and lots of kinds of drones are commercially available.
Using a commercially available drone is a mistake. These things should be designed so that they can't be jammed and they can't be damaged by a microwave beam weapon.
I'm not sure how much RC modeling you've done, but the drones are radio-controlled. You can't harden a radio-controlled device against microwaves. These days, radios utilize frequency-hopping technology, but that can't prevent jamming.
These things should be designed so that they can't be jammed and they can't be damaged by a microwave beam weapon.
These are controlled by two means: Radio and GPS. You can't prevent jamming or being shot down by a microwave without spending millions of dollars to harden the equipment and encrypt the communication.