The video shows it was a ‘do you think’ question. Pompeo did not initiate the conversation. He just said it was possible. What was he to say? CNN is doing their fine work of twisting things again.
That's why the question was ludicrous. When you ask a question about God's intentions, a lot of things are "possible."
If the reporter asked Pompeo if God wanted Iran and Israel to destroy each other, an honest answer to that question would also have to be: "It's possible." Right?