Posted on 01/03/2019 10:14:10 AM PST by Bob434
Cancer Research UK recruits first patients in trial to improve the early detection and diagnosis of different cancer types Study will use Owlstone Medicals Breath Biopsy platform to identify breath biomarkers to detect and differentiate early-stage disease Study will recruit 1,500 patients at Addenbrookes Hospital, Cambridge
Cambridge, UK, January 3rd 2019: Owlstone Medical (or the Company), a global diagnostics company developing a breathalyzer for applications in early disease detection and precision medicine, and Cancer Research UK, today announces the clinical launch of the PAN Cancer trial for Early Detection of Cancer in Breath1, with the first patients now being recruited for the 1,500 patient study.
As previously announced on initiation of the collaboration, researchers in the trial are using Owlstone Medicals2 Breath Biopsy® platform to collect samples, including healthy individuals as trial controls, to analyze volatile organic compounds (VOCs) in the breath. The trial aims to identify VOCs that can be used as breath-based biomarkers to detect and differentiate different cancer types, thereby improving early detection.
This approach holds great promise as cancer cells display altered metabolism even at the very earliest stage of disease, affecting the pattern of the VOCs exhaled. By identifying the changing pattern of VOCs early, Owlstone Medicals Breath Biopsy technology could detect cancer at the earliest stage of disease, when treatments are more effective and more lives can be saved.
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