I’m a female, and I never took my Sam Brown belt off, or removed my weapon from the holster when I was carrying, and had to go to the bathroom. The only mishap I ever had going to the bathroom was forgetting I had stuffed one end of a pair of hand cuffs into the back of my uniform pants, and hearing the tell-tale clunk of cuffs falling into the toilet.
I bet the next suspect you cuffed appreciated that.
And then you’re faced with the dilemma that others have faced in the same situation - do you fish them out or leave them and replace them secretly.
https://www.youtube.com/watch?v=a9XRwSA8_Qc