The whole purpose of the clause was to give the Congress a way to prevent the States from using their regulatory powers in ways to the detriment citizens of other States.
It wasn’t even about making rules to govern the activities of private Persons or privately held entities as they sought to engage in commerce among the several States, for those doing so would still be covered by the Laws of all the States they were conducting business in when they were doing business within them.
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The whole purpose of the clause was to give the Congress a way to prevent the States from using their regulatory powers in ways to the detriment citizens of other States.
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Strike Citizens and I believe we’re on the same page.
What it DOESN’T mean is *controlling* every aspect of interstate commerce.
Much like the interstate road system, the States may have an overseer (everyone agrees/plays by same set of rules), but they don’t need/require a Lord.