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AP Exclusive: US scientists try 1st gene editing in the body
AP ^ | MARILYNN MARCHIONE

Posted on 11/15/2017 9:00:16 AM PST by RoosterRedux

Scientists for the first time have tried editing a gene inside the body in a bold attempt to permanently change a person’s DNA to cure a disease.

The experiment was done Monday in California on 44-year-old Brian Madeux. Through an IV, he received billions of copies of a corrective gene and a genetic tool to cut his DNA in a precise spot.

“It’s kind of humbling” to be the first to test this, said Madeux, who has a metabolic disease called Hunter syndrome. “I’m willing to take that risk. Hopefully it will help me and other people.”

Signs of whether it’s working may come in a month; tests will show for sure in three months.

If it’s successful, it could give a major boost to the fledgling field of gene therapy . Scientists have edited people’s genes before, altering cells in the lab that are then returned to patients. There also are gene therapies that don’t involve editing DNA.

But these methods can only be used for a few types of diseases. Some give results that may not last. Some others supply a new gene like a spare part, but can’t control where it inserts in the DNA, possibly causing a new problem like cancer.

(Excerpt) Read more at apnews.com ...


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1 posted on 11/15/2017 9:00:16 AM PST by RoosterRedux
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To: RoosterRedux

What could possibly go wrong?.............................

2 posted on 11/15/2017 9:01:51 AM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: RoosterRedux

3 posted on 11/15/2017 9:03:14 AM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: RoosterRedux

Hopefully it will help him, though I dont know what HS is.


4 posted on 11/15/2017 9:03:24 AM PST by wyowolf (Be ware when the preachers take over the Republican party...)
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To: RoosterRedux

Have you ever taken that test yourself, Mr. Deckard?


5 posted on 11/15/2017 9:03:51 AM PST by HLPhat ("TO SECURE THESE RIGHTS" -- Government with any other purpose is not American.)
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To: Red Badger

6 posted on 11/15/2017 9:04:08 AM PST by dfwgator
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To: wyowolf

https://en.wikipedia.org/wiki/Hunter_syndrome


7 posted on 11/15/2017 9:04:48 AM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Red Badger
>>What could possibly go wrong?.............................


8 posted on 11/15/2017 9:05:05 AM PST by HLPhat ("TO SECURE THESE RIGHTS" -- Government with any other purpose is not American.)
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To: Red Badger
What could possible go wrong?

Everything. I'm wondering how far we are from blended species....humans with some gorilla DNA for strength etc. I wonder if there's some secret research along those lines going on already.

9 posted on 11/15/2017 9:05:28 AM PST by grania (Deplorable and Proud of It!)
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To: grania

Most likely....................very secret...................Planet of the Apes very secret.................


10 posted on 11/15/2017 9:06:45 AM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Red Badger

Hunter syndrome, or mucopolysaccharidosis II (MPS II), is a lysosomal storage disease caused by a deficient (or absent) enzyme, iduronate-2-sulfatase (I2S).[1][2] The accumulated substrates in Hunter syndrome are heparan sulfate and dermatan sulfate.[3] The syndrome has X-linked recessive inheritance.[3]

Thank you thats much clearer now...


11 posted on 11/15/2017 9:09:12 AM PST by wyowolf (Be ware when the preachers take over the Republican party...)
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To: grania

That is the goal. The left wants every organism on planet earth to be the same.


12 posted on 11/15/2017 9:11:44 AM PST by libh8er
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To: RoosterRedux

I can remember this being talked about in the 1970’s...and it was directed at Downs Syndrome.


13 posted on 11/15/2017 9:15:17 AM PST by Sacajaweau
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To: RoosterRedux

I’m not a biologist nor do I play one on TV, but how does injecting billions of genes affect trillions of cells in the human body? How do they even get into the cell? And if all this is possible, is it possible to cure the defective gene that causes liberalism?


14 posted on 11/15/2017 9:15:56 AM PST by GrandJediMasterYoda (Trump: Greatest POTUS of all time solely for preventing Satan from taking office.)
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To: grania

Much more lucrative to use steroids. I’m sure there’s a black market.


15 posted on 11/15/2017 9:17:25 AM PST by Sacajaweau
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To: GrandJediMasterYoda

There’s a short video at source that explains that...sort of.


16 posted on 11/15/2017 9:18:03 AM PST by RoosterRedux
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To: RoosterRedux

GMO people.

Will it be permissible to boycott GMO people in dating, marriage, insurance, and employment?


17 posted on 11/15/2017 9:18:54 AM PST by a fool in paradise (Did Barack Obama denounce Communism and dictatorships when he visited Cuba as a puppet of the State?)
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To: Red Badger

That was the most horrifying and gruesome movie scene I had ever seen when it came out. And it still ranks right up there!


18 posted on 11/15/2017 9:20:29 AM PST by ProtectOurFreedom
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To: grania
LOTS of research in these areas going on and it's not all hidden in secret. The Chinese are creating super-muscle dogs -- many observers think its for their military applications. Think of soldiers looking like this!

Google "Human Chimera Research" for some real scary stuff!

19 posted on 11/15/2017 9:26:26 AM PST by ProtectOurFreedom
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To: RoosterRedux
Hunter Syndrome
20 posted on 11/15/2017 9:38:37 AM PST by Slyfox (Are you tired of winning yet?)
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