I think she will try to talk to "facts", be the policy wonk, which bolsters her lifelong qualifications to be president. Trump will tear these apart, talk right over and past her about the raw emotions, the populism and nationalism that he realizes are more important to the voters. We, speaking for myself, don't care about the details of the wall so long as it is built. I don't care how he and the military defeat Islam so long as it is done, Blacks won't care about fixing urban areas so long as it done. This is what I suspect Clinton and the media, so attuned to specifics they can pick apart, don't understand. Clinton be Clinton, Trump be Trump, he wins. Jeb threw money at his attempt and failed spectacularly, Clinton is repeating the same.
Her biggest challenge and prep is to simply survive from a health and breathing perspective. Media will give her points for that before looking further.