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New kind of "designer" immune cells clear baby's leukaemia
Reuters ^ | 5 Nov 2015 | Kate Kelland

Posted on 11/05/2015 1:13:06 PM PST by amorphous

A baby whom doctors thought almost certain to die has been cleared of a previously incurable leukemia in the first human use of an "off-the-shelf" cell therapy from Cellectis that creates designer immune cells.

One-year-old Layla had run out of all other treatment options when doctors at Britain's Great Ormond Street Hospital (GOSH) gave her the highly experimental, genetically edited cells in a tiny 1-milliliter intravenous infusion.

Two months later, she was cancer-free and she is now home from hospital, the doctors said at a briefing about her case in London on Wednesday.

"Her leukemia was so aggressive that such a response is almost a miracle," said Paul Veys, a professor and director of bone marrow transplant at GOSH who led the team treating Layla.

"As this was the first time that the treatment had been used, we didn't know if or when it would work, so we were over the moon when it did."

(Excerpt) Read more at reuters.com ...


TOPICS: Culture/Society; Front Page News
KEYWORDS: genes; leukemia; medical; scientists
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I have a dear friend with leukemia. I hope it can made available to everyone soon!
1 posted on 11/05/2015 1:13:06 PM PST by amorphous
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To: amorphous

i think with modern technology this is the real deal, but i feel like i’ve been reading, ever since i could read, about this or that treatment that cured cancer.

perhaps it has come a long way in 40 years.

GF had breast cancer and surgery and chemo were used. just like 40 years ago.


2 posted on 11/05/2015 1:18:16 PM PST by dp0622
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To: amorphous

Great news.


3 posted on 11/05/2015 1:18:37 PM PST by sparklite2 (All will become clear when it is too late to matter.)
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To: amorphous

Promising.


4 posted on 11/05/2015 1:21:40 PM PST by free_life (If you ask Jesus to forgive you and to save you, He will.)
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To: amorphous

As my wife died young of liver cancer, I am always happy to hear of breakthroughs in treatment.

That said, this is pretty scary stuff and I cannot help but think of how wrong this could go in a Resident Evil sort of way.


5 posted on 11/05/2015 1:30:03 PM PST by Norm Lenhart (Existential Cage Theory - Embrace it)
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To: dp0622

But the drugs have changed, the management of nausea is better, but still you are right. You’d think it would be farther toward a cure or vaccine by now. I had BC myself but only had to have radiation and have passed the big 5 yr mark clean as a whistle. People knock mammograms, but that is what saved me.


6 posted on 11/05/2015 1:30:03 PM PST by buckeye49 (HOPE IS NOT A STRATEGY-TED CRUZ FOR PRESIDENT!!)
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To: amorphous

Wow wow wow!!!!


7 posted on 11/05/2015 1:30:47 PM PST by Scutter
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To: dp0622
I think we would be much further along in the field of medicine if there were far less regulation.

IMO, government regulation and the AMA has contribute to greater numbers dying from illnesses than not.

I believe the cure to be a mega dose of deregulation.

8 posted on 11/05/2015 1:31:56 PM PST by amorphous
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To: amorphous

A friend of mine got transfusions from his brother and they both came out of it okay. Though he now has curly hair like his brother.


9 posted on 11/05/2015 1:31:59 PM PST by Sacajaweau
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To: amorphous

This is an exciting development.


10 posted on 11/05/2015 1:33:11 PM PST by TigersEye (This is the age of the death of reason and rule of law. Prepare!)
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To: Norm Lenhart
Sorry to hear Norm. Can't imagine what you must have went through.

God Bless You

11 posted on 11/05/2015 1:33:46 PM PST by amorphous
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To: amorphous

Stuff happens. Hopefully this treatment will be the success it appears to be.


12 posted on 11/05/2015 1:34:37 PM PST by Norm Lenhart (Existential Cage Theory - Embrace it)
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To: dp0622
GF had breast cancer and surgery and chemo were used. just like 40 years ago.

Prayers for your GF dp. Hope she is doing well and free of that most dreaded disease of women everywhere.

God Bless

13 posted on 11/05/2015 1:37:15 PM PST by amorphous
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To: Sacajaweau

Lol, that’s funny. Glad they’re doing well! :-)


14 posted on 11/05/2015 1:38:12 PM PST by amorphous
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To: Sacajaweau

Wow, sounds like my cousins. Stem cells from his brother cured him.


15 posted on 11/05/2015 1:49:17 PM PST by Marie Antoinette (:)
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To: Sacajaweau

A not terribly relevant experience from my family:

An in-law, once removed by marriage, had straight hair before chemo and radiation for lymphoma. Fortunately, it was successful, but her hair came back in curly.

Maybe it wasn’t the transfusion that caused the change in hair texture, but rather some other part of the treatment?


16 posted on 11/05/2015 1:50:55 PM PST by Pearls Before Swine
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To: amorphous

Agree with the down thread comment, how long ago could this have been possible without the crippling regulations laid on everything by the feds.


17 posted on 11/05/2015 1:56:39 PM PST by doorgunner69
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To: buckeye49

Blame over-regulation and a centrally planned healthcare market from the local to the national level. It’s anti-innovation. You cannot even take experimental drugs if you’re terminal without government permission.

We need to start with a market for blood and kidneys. Then we’ll at least begin to relieve the shortages there.


18 posted on 11/05/2015 2:00:28 PM PST by 1010RD (First, Do No Harm)
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To: doorgunner69

Yep


19 posted on 11/05/2015 2:14:03 PM PST by amorphous
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To: Pearls Before Swine

That’s not uncommon after chemo. The hair may regrow but it can be very curly and/or wiry (tough and thin), and a completely different colour as well - even when it had previously gone grey!


20 posted on 11/05/2015 2:20:04 PM PST by Mr Radical
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