Fuel up, load all the bomb racks and missile pods, fly over target of opportunity, drop and launch everything, return to base, repeat.
Like the air raids from England over Germany and back, during WW II, where the first planes returning were meeting the last planes taking off.
Keep ‘em flying.
In contrast, it's been reported that American pilots flying missions against ISIS have been trying to respond to desperate calls for air support on the ground, but their requests are either denied or are just sat on in limbo as pending an authorization that never comes .
At some point 80-90 percent of the flights ended up returning to land with the same ordnance load it took off with.