The War on Pot provides a significant part of the incentive to use the newest garage-lab cr@p ... since the better understood pot is legally punished whereas the law will by definition always be one step behind the garage chemists.
These aren’t garage labs. This stuff is being mass produced in China. DEA has the responsibility for pushing each drug through the process of being placed on a schedule that makes it illegal. Over the time it takes that process to happen the manufacturers alter the composition. If we want to stop this we need to stop the importation of this class of useless compounds. People sure aren’t using them for incense and potpourri.