“Do you realize how rare such people are?”
It’s unclear what you mean by using “such people” as a reference. My comment began by observing that 100% of human males begin their fetal development in the first seven weeks from conception with a female genital anatomy. This initial female genital anatomy is transformed into a male only if and when a sufficient number of the subsequent required developmental stages are successfully completed to result in a full physical and mental transformation to a male. So, in that context there is nothing rare about 100% of all males being subject to this developmental requirement.
“And even then, that the only chromosomal defect that results in feminized men is Klinefelter’s?”
That is a false statement. With respect to the development of males you are denying the existence of:
Partial Androgen Insensitivity Syndrome (PAIS). People with the 46 XY karyotype develop ambiguous genitalia, and medical doctors will perform corrective surgery on the infant and thereby assign to child to a physical gender identity without regard to the child’s actual mental gender identity.
Swyer Syndrome. People with an XY karyotype are born without functioning sexual gonads (XY gonadal dysgenesis). Such a person develops the appearance of a female due to the inability to virilize, whether or not the mental gender identity is male or female.
Mosaicism. During the embryonic development the cells fail to divide properly, so the infant is born with a mix or mosaic of cells having different chromosomal karyotypes, including 46, XY/ and another karyotype. Depending on the mosaic of karyotypes, a variety of sexual and gender types will result.
“The issues with transgenders are hugely mental issues, not physical.”
Mental functionality is fundamentally governed by physical organization, especially so when the hormonal mechanisms are involved. The extent to which physiology determines mental gender identities and behavior is at a rudimentary stage of research and remains poorly investigated and understood with respect to mechanisms and consequences.