No, can’t shut own highways...but it’s a lot harder to infect multitudes from a car and the number of people who will take a bus are limited and seems to me a train has a limited area compared to a plane.
As for the economy - if we have massive ebola infections a lot more than the economy will take the hit.
” but it’s a lot harder to infect multitudes from a car....”
But people stop at gas stations, hotels/motels, restaurants along the way.