Paul’s attitude would be fine, if our borders were sealed, and if we were prepared to pay the economic price of doing so. (There are economic benefits to free trade—comparative advantage and all that.)
The Muslim world should be quarantined. No travel in or out, no trade in or out. We have plenty of oil and gas. Systematic deportation of Muslims should follow. Secular, moderate, unserious Muslims only should be allowed to stay.
It would mean more than that. It would mean no trade whatsoever because as soon as you have trade with other countries you consequently create a national interest which you want to protect.
And even if you manage to isolate yourself from the rest of the world the rest of the world may not want you isolated - sort of what we did to Japan when they wanted to be left alone.