[Eric in the Ozarks]

The Missouri GOP in and around Springfield refused to back Jim Talent for reelection, thus giving us Claire McCackle’s first term. Several historians have scrutinized the votes in SW Missouri and concluded it was Talent's support for medical research that caused a revolt in the GOP.
As far as Akin goes, he did the job on himself.

[DManA]

Talent’s support for medical research

Could you expand on that? Stem cells?