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To: austinmark; FreedomCalls; IslandJeff; JRochelle; MarMema; Txsleuth; Newtoidaho; texas booster; ...
Diabetes discovery: Protein pathway points to possible treatment A different version of the TXNIP story

Plant protein regulates diabetes treatment Not ready for prime time, but it could be a future drug delivery system.

FReepmail me if you want on or off the diabetes ping list.

N.B. Press releases at ScienceDaily usually link the abstract of the original citation after the reference to it with its DOI.

4 posted on 08/28/2013 1:46:42 PM PDT by neverdem (Register pressure cookers! /s)
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To: neverdem

Thanks, very interesting. Thus the road to diabetes starts with having to deal with too much sugar, and enough of this starts a cascade of consequences. Simplest preventative seems to be to cut out the sugar long before the problem becomes apparent. Paleo diet for anyone over 40 it seems.

“Shalev said that for some people, excessive demand on beta cells to produce insulin to counteract elevated blood sugar — which is what’s seen in type 2 diabetes, which accounts for more than 90 percent of all diabetes — eventually stresses the beta cells, which then lose their ability to make enough insulin to meet demand. This leads to an increase in blood sugar and greater levels of TXNIP production – a vicious cycle that results in even less insulin production and more beta cell death.
“Sugars in the diet per se do not cause diabetes, and we have to be cautious not to oversimplify a complex disease such as diabetes,” Shalev told LiveScience.
However, elevated blood sugar levels are known to cause an increase in TXNIP, and over time, even small increases in blood sugar levels can lead to accumulation of TXNIP and the associated beta cell dysfunction and death that can eventually lead to diabetes, she said.”


13 posted on 08/28/2013 2:39:06 PM PDT by buwaya
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