Fortunately, they mostly opted for the lower latitudes.
Organized Catholics were in Maryland in the 1640’s and holding worship services and had settlements in Florida in the 1500’s. Many were here even before that. Catholics are very much interwoven into the fabric that is early North America. I have Catholic relatives that came from France, to Canada, to northern NY in the 1700’s. In my line they intermarried with German Lutherans, and English Baptists that arrived in the 1600’s. I grew up Catholic and we are all very conservative and traditional. Don’t believe all the anti-Catholic propaganda, it just pulls Christians farther apart, which is what certain groups want.