For the power given to Congress by the Constitution does not extend to the internal regulation of the commerce of a State, (that is to say of the commerce between citizen and citizen,) which remain exclusively (emphases added) with its own legislature; but to its external commerce only, that is to say, its commerce with another State, or with foreign nations, or with the Indian tribes. Thomas Jefferson, Jeffersons Opinion on the Constitutionality of a National Bank : 1791."State inspection laws, health laws, and laws for regulating the internal commerce of a State, and those which respect turnpike roads, ferries, &c. are not within the power granted to Congress (emphases added)." --Gibbons v. Ogden, 1824.
Base on a discussion in a related thread, possibly the reason that businessmen comply with constitutionally indefensible federal minimal wage laws is because they don't understand Congress's Section 8-limited powers imo.
They do understand, though, that the Federal Government will use every power it is, legal or illegal, to destroy them if they don’t comply with whatever it says.