An allergic reaction requires protein. There is no protein in cigarette smoke.
What these "some people" are experiencing, in your anecdotal opinion is a panic attack, or what physicians used to call "hysteria". Those same "physicians" treated "hysteria" with dildoes and vibrators.
What would you prefer?
Sorry, an allergic reaction does not require protein. Where did you get that? Drugs and dust can also cause allergic reactions, and they are not proteins. How about you stuff a dildo up your stupid lewd mouth and a vibrator out the other end? What a jerk!