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New drug being developed ... 'could help humans live until they are 150'
http://www.dailymail.co.uk/health/article-2291254/New-drug-developed-using-compound-red-wine-help-humans-live-150.html ^ | 6:40 EST, 10 March 2013 | Lucy Crossley

Posted on 03/10/2013 7:51:21 PM PDT by null and void

The new drugs are synthetic versions of resveratrol which is found in red wine and is believed to have an anti-ageing effect as it boosts activity of a protein called SIRT1.

Pharmaceutical giant GlaxoSmithKline has been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease.

The work proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.

The most common naturally-occurring activator is resveratrol, which is found in small quantities in red wine, but synthetic activators with much stronger activity are already being developed.

Despite this, there have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.

Professor Sinclair said: 'In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster.'

Four thousand synthetic activators, which are 100 times as potent as a single glass of red wine, have been developed - with the best three being used in human trials.

While any drug would be strictly prescribed for certain conditions, Professor Sinclair suggests that one day, they could be taken orally as a preventative.

They could therefore be used in the same way as statin drugs are commonly prescribed to prevent, instead of simply treating, cardiovascular disease.

In animal models, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.

'Some of us could live to 150, but we won't get there without more research.'

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Culture/Society
KEYWORDS: aging; antiaging; brzenzski; davosplayers; elite; elitecancerfree; kissenger; lifextension; nwo; resveratrol; soros
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Here's to 100 more years of the Obama presidency...
1 posted on 03/10/2013 7:51:21 PM PDT by null and void
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To: null and void

Just think...90 years of sagginess.


2 posted on 03/10/2013 7:52:20 PM PDT by BenLurkin (This is not a statement of fact. It is either opinion or satire; or both)
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To: null and void

Why would I want to live until 150?


3 posted on 03/10/2013 7:52:24 PM PDT by Darren McCarty (If most people were more than keyboard warriors, we might have won the election)
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To: null and void
already being done, by some


4 posted on 03/10/2013 7:55:33 PM PDT by llevrok (Keep your arms out. It makes it harder for them to throw a net over you.)
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To: null and void
150 year-old parents with a lazy, jobless 125 year-old son still living in the basement, eating pizza and playing video games.
5 posted on 03/10/2013 7:58:16 PM PDT by JPG (Stay strong.)
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To: null and void

> New drug being developed ... ‘could help humans live until they are 150’

Big deal, I’m 149 now. - Helen Thomas.


6 posted on 03/10/2013 7:59:22 PM PDT by Jyotishi (Seeking the truth, a fact at a time.)
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To: null and void

"..you think it's easy climbing into a liter box at 82?...???...that's when I can remember where da ell it is"

7 posted on 03/10/2013 8:06:16 PM PDT by Doogle (USAF.68-73..8th TFW Ubon Thailand..never store a threat you should have eliminated))
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To: null and void

Don’t want it!!!

Only put away enough to last me until i’m 100!

After that my will says “being of sound mind i spent it”!


8 posted on 03/10/2013 8:06:59 PM PDT by dalereed
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To: null and void

I always try out a wide variety of nutritional supplements. A lot of them, I try for two months and see if I can notice an improvement. Others, I take based on recent scientific research. I take Resveratrol for the the latter reason. Maybe it takes a while to notice that your life has been extended by 20 years, or whatever!


9 posted on 03/10/2013 8:07:03 PM PDT by Fractal Trader
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To: null and void
...could help humans live until they are 150.

That oughta create a surge in Viagra sales.

10 posted on 03/10/2013 8:07:46 PM PDT by smoothsailing
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To: Darren McCarty

It depends on how much vitality you have. If you’re going to be the equivalent of 90 years old, for the next 60 years, you may not want it. However, if it helps you slow down your age so you don’t age as quick, it might be nice to be 80, but have the vitality of a healthy 55 year old.


11 posted on 03/10/2013 8:13:22 PM PDT by Jonty30 (What Islam and secularism have in common is that they are both death cults)
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To: null and void

Will this be offered in a time-release capsul?


12 posted on 03/10/2013 8:13:54 PM PDT by umgud
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To: null and void
Heres the catch:
there is a definative, working product,
it will only be affordable by the likes of Gates, Bloomberg, Soros, etc...
13 posted on 03/10/2013 8:13:55 PM PDT by 45semi (A police state is always preceded by a nanny state...)
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To: llevrok
After mistaken reports of his death in 1982 and 1987, Vigoda has been the subject of running gags as to whether he is dead or alive. Good naturedly, he made regular appearances on television shows to make fun of the error.

He looked like he was the walking dead when he acted in Barney Miller. I am surprised he is still alive.

14 posted on 03/10/2013 8:15:13 PM PDT by Robert DeLong (u)
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To: null and void
I'm not sure I want to live that long.


15 posted on 03/10/2013 8:16:22 PM PDT by smokingfrog ( ==>sleep with one eye open (<o> ---)
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To: null and void
I've got cigars and ammo that will last another 90 years...I want to be here to enjoy them.

That said, exercise is a must if you are to remain virile for 150 years...you might even need some testosterone supplements...and a little bit of bran every day.

16 posted on 03/10/2013 8:16:41 PM PDT by RoosterRedux (Get armed, practice in the use of your weapons, get physically fit, stay alert!)
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To: 45semi

I don’t think Soros has blood running through his veins. I don’t know what it is, but the man just won’t die.


17 posted on 03/10/2013 8:16:59 PM PDT by Jonty30 (What Islam and secularism have in common is that they are both death cults)
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To: null and void

Why?


18 posted on 03/10/2013 8:18:16 PM PDT by SkyDancer (Live your life in such a way that the Westboro church will want to picket your funeral.)
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To: Fractal Trader
key is not to under-dose on resveratrol and these other new drugs. who wants to get old? dying not as bad as getting and being old imo
19 posted on 03/10/2013 8:18:53 PM PDT by Democrat_media (media makes mass shooters household names to create more & take our guns)
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To: null and void
and they think Social Security has problems now...
20 posted on 03/10/2013 8:19:41 PM PDT by Chode (Stand UP and Be Counted, or line up and be numbered - *DTOM* -ww- NO Pity for the LAZY)
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To: 45semi

It’s always that way at first, but the draw of being able to sell a billion pills for $5 a pop, as opposed to 1,000 pills at $10,000 a pop, always wins out.


21 posted on 03/10/2013 8:20:18 PM PDT by Jonty30 (What Islam and secularism have in common is that they are both death cults)
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To: null and void

Genesis 6:3
And the Lord said, My spirit shall not always strive with man, for that he also is flesh: yet his days shall be an hundred and twenty years.


22 posted on 03/10/2013 8:20:28 PM PDT by donna (Pray for revival.)
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To: Democrat_media
dying not as bad as getting and being old imo

You've done both?

23 posted on 03/10/2013 8:23:44 PM PDT by Alaska Wolf (I)
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To: Pride in the USA

ping


24 posted on 03/10/2013 8:24:07 PM PDT by lonevoice (Today I broke my personal record for most consecutive days lived)
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To: donna

It’s been shown that aging is mostly environmental in nature. That’s why some 80 year olds act like they’re fifty and other 80 year olds are very decrepit.

If you can minimize the environmental factors, there’s no reason why cell death (the real cause of aging) can’t be slowed down and people live longer as a result.


25 posted on 03/10/2013 8:28:37 PM PDT by Jonty30 (What Islam and secularism have in common is that they are both death cults)
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To: null and void

Gonna confound Obama’s death panels.


26 posted on 03/10/2013 8:32:45 PM PDT by izzatzo (NO MORE BUSHES!)
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To: Jonty30
Guess thats true, unless the company(s) become 'nationalized' & only the 'elite' have access...
(yes, thats my pessimistic side showing, seen too many sci-fi movies I guess!)
27 posted on 03/10/2013 8:32:50 PM PDT by 45semi (A police state is always preceded by a nanny state...)
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To: Fractal Trader

We take resveratrol every day via the red wine. After a couple of glasses we feel younger already. :-)


28 posted on 03/10/2013 8:35:36 PM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped.)
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To: Chode

Oh sure...like a wet blanket on a cold rainy night.


29 posted on 03/10/2013 8:38:39 PM PDT by ROCKLOBSTER (Hey RATS! Control your murdering freaks.)
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To: null and void

[[New drug being developed ... ‘could help humans live until they are 150’]]

[[Here’s to 100 more years of the Obama presidency... ]]

I was just goign to say abotu hte same hting- who the hell wants to live that long in a coutnry where our basic consitutional rights are beign taken away almsot daily now? in NY you have goverrnors and mayors trampling all over their citizen’;s rights tellign them what they can eat, what they can and can’t drink, what they can use for self protection on and on and on- in cali you have the government there contemplating banning smoking in people’s own homes for crying out loud- and for htose that think ‘Ther’s no way they can or will enforce it’ think again=- kids will be asked at health exams “Do you parents smokes? Do they smoke in the house?” and if the answer is yes, then law enforcement WILL BE CALLED and sent to the home with an arrest warrant for ‘potential endagering the wealfare of a child’- and you mark my words- there WILL come hte day when health officials WILL ASK kids what they eat at home, and if it’s not wholesome foods or too much junk food- hte parents may very well face similiar charges-

‘Can’t ever happen’? It IS happenign folks- nope- I sure as hell don’t care to live 150 years-


30 posted on 03/10/2013 8:45:06 PM PDT by CottShop (Scientific belief does not constitute scientific evidence, nor does it convey scientific knowledge)
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To: donna

[[Genesis 6:3
And the Lord said, My spirit shall not always strive with man, for that he also is flesh: yet his days shall be an hundred and twenty years.]]

No no no- these scientisits are like little gods- they can build towers that reach way into the heavens- it’s been doen before- oh wait- NM- no it hasn’t


31 posted on 03/10/2013 8:48:34 PM PDT by CottShop (Scientific belief does not constitute scientific evidence, nor does it convey scientific knowledge)
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To: ROCKLOBSTER
pretty much...
32 posted on 03/10/2013 8:48:49 PM PDT by Chode (Stand UP and Be Counted, or line up and be numbered - *DTOM* -ww- NO Pity for the LAZY)
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To: Fractal Trader
I take Resveratrol for the the latter reason. Maybe it takes a while to notice that your life has been extended by 20 years, or whatever!

You're already seeing it - you were supposed to die 10 years ago.
33 posted on 03/10/2013 8:48:56 PM PDT by fr_freak
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To: donna

That further got reduced to 70 years, or 80 with a great constitution.

It’s a general rule, obviously there are things you can do to not have your body fail you, and if you avoid deadly accidents,...


34 posted on 03/10/2013 9:00:26 PM PDT by Secret Agent Man (I can neither confirm or deny that; even if I could, I couldn't - it's classified.)
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To: Democrat_media

I tried messing around with topical applications of estriol cream recently too even though I am not yet menopausal until it sort of dawned on me that even with progesterone balance, extended use could be an nice way to possibly give myself breast cancer. I think I hold the resveratrol until the long-term effects of high doses of are better known.


35 posted on 03/10/2013 9:11:37 PM PDT by erlayman
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To: erlayman

Meanwhile, you could drink an awful lot of red wine.


36 posted on 03/10/2013 9:14:03 PM PDT by ROCKLOBSTER (Hey RATS! Control your murdering freaks.)
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To: null and void

Not going to happen if Obama has any say!


37 posted on 03/10/2013 9:25:50 PM PDT by Deagle (quo)
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To: Doogle

Santa Claws?


38 posted on 03/10/2013 9:39:57 PM PDT by Kickass Conservative (A Republican freed the Slaves and a Democrat murdered Martin Luther King.)
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To: null and void

There’s one huge difference between the rats they use in these studies and the people they ultimately hope will benefit from these drugs - the rats eat food.

Most people eat processed crap that has only a vague resemblance to actual food.

It may be that these drugs might have some benefit, but I’d be very surprised if they’d be powerful enough to the thousands of calories of junk people eat every day.


39 posted on 03/10/2013 9:57:54 PM PDT by jdege
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To: null and void

No economy could sustain any significant population at that extreme age. Look at the situation we have now...


40 posted on 03/10/2013 10:15:43 PM PDT by newzjunkey (bah)
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To: null and void

Imagine having to listen to Jimmy Carter natter on about his crap for another 70 years.


41 posted on 03/11/2013 12:03:55 AM PDT by ModelBreaker
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To: Chode
and they think Social Security has problems now...

They'll just bump the age to claim it up to 145 or so...

42 posted on 03/11/2013 2:29:46 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: izzatzo
“Gonna confound Obama’s death panels.”

Nah. Only the political elite will have the drug. Obama’s death panels will have to shorten the lives of the rest of us to make up for the increased resource usage by the then longer lived political elite.

43 posted on 03/11/2013 2:45:44 AM PDT by PIF (They came for me and mine ... now it is your turn ...)
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To: Kickass Conservative

kkk....kris kringle kat


44 posted on 03/11/2013 3:00:28 AM PDT by Doogle (USAF.68-73..8th TFW Ubon Thailand..never store a threat you should have eliminated))
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To: null and void

“Grandfather, it’s not healthy to live to be such an old age” {Windwalker}


45 posted on 03/11/2013 3:32:14 AM PDT by cva66snipe (Two Choices left for U.S. One Nation Under GOD or One Nation Under Judgment? Which one say ye?)
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To: null and void

Absolute total disaster unless they are able to stop all dementia, Alzheimers, and related neurological breakdowns first.

I can not imagine dealing with a dementia patient for 80+ years.


46 posted on 03/11/2013 3:44:31 AM PDT by wrench
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To: Darren McCarty

“Why would I want to live until 150?”

Why not...if you were healthy and disease free...
‘Moses’ attributes (Deuteronomy 34:7)...
Fully ambulatory...
Jack LaLane abs...
Full mental prowess...
Eyes, ears and nose fully functional...

‘And Moses was an hundred and twenty years old when he died: his eye was not dim, nor his natural force abated.’
(Deuteronomy 34:7 KJV)


47 posted on 03/11/2013 3:48:01 AM PDT by GGpaX4DumpedTea (I am a Tea Party descendant...steeped in the Constitutional Republic given to us by the Founders.)
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To: erlayman

“I think I hold the resveratrol until the long-term effects of high doses of are better known.”

But it might take 150 years or so to find out if it works...you gotta try it to know... :)

Meanwhile, Pino Noir has the most of the good resveratrol stuff...a glass every hour or so could make life a lot more interesting while you wait to decide on the ‘treatment’...


48 posted on 03/11/2013 3:53:34 AM PDT by GGpaX4DumpedTea (I am a Tea Party descendant...steeped in the Constitutional Republic given to us by the Founders.)
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To: Smokin' Joe
no doubt... and people over 50 think they have a hard time getting work, try looking for work at 100
49 posted on 03/11/2013 4:51:35 AM PDT by Chode (Stand UP and Be Counted, or line up and be numbered - *DTOM* -ww- NO Pity for the LAZY)
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To: Darren McCarty
Why would I want to live until 150?

At his 70th birthday party, Ike quipped, "People ask, 'Who wants to live to be 100?'.....the man who's 99."

50 posted on 03/11/2013 5:25:40 AM PDT by Roccus
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