Skip to comments.New drug being developed ... 'could help humans live until they are 150'
Posted on 03/10/2013 7:51:21 PM PDT by null and void
The new drugs are synthetic versions of resveratrol which is found in red wine and is believed to have an anti-ageing effect as it boosts activity of a protein called SIRT1.
Pharmaceutical giant GlaxoSmithKline has been testing the medications on patients suffering with medical conditions including cancer, diabetes and heart disease.
The work proves that a single anti-ageing enzyme in the body can be targeted, with the potential to prevent age-related diseases and extend lifespans.
The most common naturally-occurring activator is resveratrol, which is found in small quantities in red wine, but synthetic activators with much stronger activity are already being developed.
Despite this, there have already been promising results in some trials with implications for cancer, cardiovascular disease and cardiac failure, type 2 diabetes, Alzheimer's and Parkinson's diseases, fatty liver disease, cataracts, osteoporosis, muscle wasting, sleep disorders and inflammatory diseases such as psoriasis, arthritis and colitis.
Professor Sinclair said: 'In the history of pharmaceuticals, there has never been a drug that tweaks an enzyme to make it run faster.'
Four thousand synthetic activators, which are 100 times as potent as a single glass of red wine, have been developed - with the best three being used in human trials.
While any drug would be strictly prescribed for certain conditions, Professor Sinclair suggests that one day, they could be taken orally as a preventative.
They could therefore be used in the same way as statin drugs are commonly prescribed to prevent, instead of simply treating, cardiovascular disease.
In animal models, overweight mice given synthetic resveratrol were able to run twice as far as slim mice and they lived 15 per cent longer.
'Some of us could live to 150, but we won't get there without more research.'
(Excerpt) Read more at dailymail.co.uk ...
Just think...90 years of sagginess.
Why would I want to live until 150?
> New drug being developed ... ‘could help humans live until they are 150’
Big deal, I’m 149 now. - Helen Thomas.
"..you think it's easy climbing into a liter box at 82?...???...that's when I can remember where da ell it is"
Don’t want it!!!
Only put away enough to last me until i’m 100!
After that my will says “being of sound mind i spent it”!
I always try out a wide variety of nutritional supplements. A lot of them, I try for two months and see if I can notice an improvement. Others, I take based on recent scientific research. I take Resveratrol for the the latter reason. Maybe it takes a while to notice that your life has been extended by 20 years, or whatever!
That oughta create a surge in Viagra sales.
It depends on how much vitality you have. If you’re going to be the equivalent of 90 years old, for the next 60 years, you may not want it. However, if it helps you slow down your age so you don’t age as quick, it might be nice to be 80, but have the vitality of a healthy 55 year old.
Will this be offered in a time-release capsul?
He looked like he was the walking dead when he acted in Barney Miller. I am surprised he is still alive.
That said, exercise is a must if you are to remain virile for 150 years...you might even need some testosterone supplements...and a little bit of bran every day.
I don’t think Soros has blood running through his veins. I don’t know what it is, but the man just won’t die.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.