My wife has been enduring MS for over 20 years and has been on many of the typical therapies (Avonex, Copaxone, IVIG) and, as you pointed out, the disease still progresses. She is about to start Abagio. Do you have any experience with that?
Sorry to hear about your wife’s progression. As far as Aubagio, I’ve only read threads about it on MS Forums. Here’s a thread where a poster does a pretty good job of summarizing what the drug’s about.
http://www.msworld.org/forum/showthread.php?t=121145&highlight=aubagio
My MS neuro told me to hold out for BG12...but then he left our MS center to head up the MS division of Genzyme that make Aubagio, so go figure.
I hope she does well on it, at least no more needles :)