[neverdem]

Since flumazenil antagonized the effects of benzodiazepines, they thought there were specific benzodiazepine receptors.

[wastedyears]

Did that neurologist think to recommend patients to an endocrinologist to have calcium and parathyroid levels checked?

[Myrddin]

Many years ago I was reading "The Schwartzbein Principle". Schwartzbein discussed sleep issues and said that "GABA" helps "reduce the noise in your head" so you can sleep. I often find myself writing software algorithms instead of normal "dreaming". It's very productive the next day, but often results in being damn tired instead of being rested. On a whim, I picked up a bottle of GABA to evaluate the effects. It turned my normal mental machinations into a full blown circus. A bit like the kind of rave you might see in a heavy metal night club in an over the top Hollywood movie. I certainly didn't sleep well at all. About 6 weeks later, I tested it again. Same effect. GABA does not turn down the "noise" in my head. It might as well be a brass band playing. It turns up the noise for me.

When I'm forced out of bed before I'm adequately rested, I'm tired all day. I just blew off making the 900 mile drive home for Thanksgiving because my employer sent me to a very expensive security training class, then my niece stole the only sleep day I was going to get for a memorial for her dad. 11 days of forced 6:30 AM starts with work finishing at midnight to 1 AM. I was too burned out to safely drive.

[Myrddin]

Many years ago I was reading "The Schwartzbein Principle". Schwartzbein discussed sleep issues and said that "GABA" helps "reduce the noise in your head" so you can sleep. I often find myself writing software algorithms instead of normal "dreaming". It's very productive the next day, but often results in being damn tired instead of being rested. On a whim, I picked up a bottle of GABA to evaluate the effects. It turned my normal mental machinations into a full blown circus. A bit like the kind of rave you might see in a heavy metal night club in an over the top Hollywood movie. I certainly didn't sleep well at all. About 6 weeks later, I tested it again. Same effect. GABA does not turn down the "noise" in my head. It might as well be a brass band playing. It turns up the noise for me.

When I'm forced out of bed before I'm adequately rested, I'm tired all day. I just blew off making the 900 mile drive home for Thanksgiving because my employer sent me to a very expensive security training class, then my niece stole the only sleep day I was going to get for a memorial for her dad. 11 days of forced 6:30 AM starts with work finishing at midnight to 1 AM. I was too burned out to safely drive.

[Myrddin]

FR is double posting tonight.

[spankalib]

Thanks again neverdem, your posts contain a ton of interesting info!

Myrddin...if I’m understanding correctly, what you experience with GABA supplementation is the opposite of what it’s ‘sposed to be. Like Ritalin(!?) for hyperactivity - GABA is causing a paradoxical reaction in you. That’s very interesting.
Could it be the source of supplementation that’s “off”? IDK, but I feel for you. There are lists of various GABA-containing foods, I wonder if your reaction to them would be different?
Also, I’m not as up with the research, but I wonder if it’s a GABA problem, or a hyperactive GABA RECEPTOR problem.

I agree with the poster who mentioned checking endocrine function...
just me, but I’d go for blood testing with an eye toward ‘treatment’ with whole food supplements...YMMV.
FRegards,
spank

[GBA]

Who's to say what's normal, but maybe we're not doing it right, or at least not as we used to.

Look up "First sleep and Second sleep" for another idea about how we might be wired and why some of us struggle with going back to sleep.

[neverdem]

The Hazards of Growing Up Painlessly

Detecting cancer cells and parasites

A Wet Way to Better Burning?

Doctor disputes common acceptance of ‘brain death’ The link in comment# 19 is quite a read.

FReepmail me if you want on or off my health and science ping list.