[neverdem]

"While NSAIDs have some ability to limit clotting caused by platelet aggregation, this capacity fades as the drugs wear off, she notes. In contrast, when aspirin binds to a platelet, its effect is irreversible, which is how daily aspirin suppresses stickiness in the population of platelets even as they are replenished."

I thought aspirin was an NSAID.

Aspirin is the granddaddy of modern NSAIDS. It does its trick by irreversibly inhibiting platelet aggregation.

The other NSAIDS reversibly inhibit platelet aggregation. That's why aspirin should be taken a few hours before any other NSAIDs for your aches and pains.

[Myrddin]

Method of action by aspirin

[zeestephen]

Thanks.

That explains it perfectly.