Predictably, there are now shortages of drugs in the USA, where they were previously invented, made and sold.
Why did this happen ?
It's like any cartel-induced shortage. The big drug companies had a major push over the last few years to limit competition from generics. They used various business tactics but also got help from the FDA and Congress. This was successful in improving the market for their much more expensive patented drugs, But they went a little too far and now many useful generic drugs are not available. The remaining generic makers (which are sometimes the same companies now) will bring the generics back - at higher prices.