“The laws of physics have not changed ~ the fissionable material does degrade ~ which is why we call it fissionable and why it has half-lives.”
Yes and the half life is about 10,000 years. We have such a solid state system we don’t have to worry too much. The only way it would be degrading is if it was leaking and we have sensors that monitor for it.
There are also problems involving the effect of very low levels of alpha particle emission on housings for the warheads. It's good to remanufacture the devices at regular intervals if only to replace the housings and replace the electrical detonation devices.