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Secondly, the magnetic particles show up on magnetic resonance imaging (MRI) scans, so that doctors can follow the progress of the treatment and monitor drug concentrations in the brain.

Subsequent MRI scans would be contraindicated with any magnetic implant, no? That sounds like a recipe for an instant stroke, IMHO. Methinks I'd prefer a CT scan.

Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain

You can link the FReebie pdf article from the abstract. The DOI# is lame.

1 posted on 08/09/2010 4:02:36 PM PDT by neverdem
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2 posted on 08/09/2010 5:43:53 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

Smart. Nice application.


3 posted on 08/09/2010 6:47:22 PM PDT by MontaniSemperLiberi
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To: neverdem
The effect of the ultrasound is temporary, and the barrier returns to normal after a few hours.

Yeah, but what else gets exchanged during those few hours, and what are the consequences?

Magnetic nanoparticles do show promise, though, for targeting.

4 posted on 08/09/2010 6:55:02 PM PDT by aposiopetic
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To: neverdem
"Subsequent MRI scans would be contraindicated with any magnetic implant, no? That sounds like a recipe for an instant stroke, IMHO. Methinks I'd prefer a CT scan."

I wouldn't think so. The fields for focusing the particles in place and that for MRI are probably completely different. And I would suspect that it would be possible to design the nanoparticles such that they decompose over time, releasing the iron to a soluble form. The technology for "timed release" capability is pretty mature. I think I'd prefer it to the high dose of x-rays in a CT scan.

5 posted on 08/09/2010 7:59:21 PM PDT by Wonder Warthog
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