[GovernmentShrinker]

High levels of cortisol for a long time is probably a very common cause of depression. However, the etiology is very complex.

High levels of cortisol can be bumped down by exogenous DHEA (and vice versa). Which would explain why DHEA has been found effective for mild midlife depression (and may well be found effective for others types of depression, in future studies).

[AdmSmith]

Thanks for the info. There are 90 studies with DHEA http://www.clinicaltrials.gov/ct2/results?term=DHEA

For sure DHEA is very interesting.