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Findings May Explain Gap in Cancer Survival
NY Times ^ | August 4, 2009 | RONI CARYN RABIN

Posted on 08/03/2009 10:21:47 PM PDT by neverdem

Scientists say they have made a discovery that may help explain the racial gap in cancer survival, providing clues to why white patients often outlive blacks even when they have what appear to be the same cancers.

The insights come from research at the University of Maryland into throat cancer and squamous-cell cancers of the head and neck, which have been increasing sharply in recent years, apparently because of the human papillomavirus — the same sexually transmitted virus that causes cervical cancer and is the target of a vaccine for girls.

The virus can also be spread through oral sex, causing cancer of the throat and tonsils, or oropharyngeal cancer.

The new research builds on earlier work suggesting that throat cancer tumors caused by the virus behave very differently from other throat cancers, and actually respond better to treatment. And the new research suggests that whites are more likely than blacks to have tumors linked to the virus, which may explain the poor outcomes of African-Americans with HPV-negative tumors.

University of Maryland researchers did the study after finding that their white patients with throat cancer were surviving 70 months on average, compared with 25 months for their black patients, even though all were treated at the same hospital.

The racial disparity in survival for oropharyngeal cancers explained most of the gap between blacks and whites for all head and neck cancers, the researchers said.

“We were shocked to see this in our own institution, where more than half of the patients we treat are African-American,” said Dr. Kevin J. Cullen, director of the Greenebaum Cancer Center at University of Maryland and senior author of the new study, in the September issue of Cancer Prevention Research.

Around the same time, the Maryland researchers were analyzing specimens of head and neck tumors...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: cancer; hpv; humanpapillomavirus; scchn
Racial Survival Disparity in Head and Neck Cancer Results from Low Prevalence of Human Papillomavirus Infection in Black Oropharyngeal Cancer Patients

Press Coverage

1 posted on 08/03/2009 10:21:48 PM PDT by neverdem
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To: neverdem
Is there a Clinton/Lewinsky connection here somewhere?

Cheers!

2 posted on 08/03/2009 10:23:37 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: grey_whiskers
Behavioral differences? Hmmm. This is kind of like the HIV infection rates ~ people who engage in certain practices have a higher rate of infection than those who don't.

Now just how can you throw a race card on that kind of information?

3 posted on 08/03/2009 10:28:11 PM PDT by muawiyah
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To: muawiyah
Now just how can you throw a race card on that kind of information?

I don't think you can. They were profiled for HPV, and the odds were that blacks were HPV negative.

4 posted on 08/03/2009 10:34:23 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem
Other than that we are all the same!

5 posted on 08/03/2009 10:34:45 PM PDT by I see my hands (_8(|)
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To: neverdem
The racial gap has often been explained as a result of late diagnosis among African-Americans, lack of access to care and less aggressive treatment, but experts said that in the case of oropharyngeal cancer, there appeared to be distinct biological differences between the tumors.

You mean there is no one to blame or sue?

6 posted on 08/03/2009 10:42:39 PM PDT by freespirited (The Surgeon General has determined that Harry and Louise are dangerous to your health.)
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To: neverdem
white patients outlive blacks


7 posted on 08/03/2009 10:50:20 PM PDT by libh8er
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To: grey_whiskers
Is there a Clinton/Lewinsky connection here somewhere?

Nope. As Clinton explained, what he did is not something that can be called oral sex. In contrast, this study is about oral sex. You see, it depends on what the definition of is, is.

8 posted on 08/03/2009 10:54:41 PM PDT by Talisker (When you find a turtle on top of a fence post, you can be damn sure it didn't get there on it's own.)
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To: neverdem
Virus infected stem cells from spermatozoa?

Glycoprotein molecules on the surface of sperm cells are recognised by all human immune systems, and interpreted as a signal that the cell should not be rejected. The male immune system might otherwise attack sperm whilst in the testes, and the female immune system would attack sperm in the reproductive tract. The specific glycoproteins coating sperm cells are also utilized by some cancerous and bacterial cells, some parasitic worms, and HIV-infected white blood cells, in order to avoid an immune response from the host organism.
9 posted on 08/03/2009 11:00:02 PM PDT by BIGLOOK (Government needs a Keelhauling now and then.)
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To: neverdem

bookmark


10 posted on 08/03/2009 11:29:26 PM PDT by GOP Poet
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To: neverdem
I can't even figure out what the report is saying.

Do they purposely write to be vague?

Are they saying that blacks are surviving for shorter periods then whites because they have more oral sex then whites?

11 posted on 08/04/2009 12:06:29 AM PDT by fortheDeclaration ("Our constitution was made only for a moral and religious people".-John Adams)
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To: fortheDeclaration
Are they saying that blacks are surviving for shorter periods then whites because they have more oral sex then whites?

No. Read it again. They infer the opposite. Blacks are more likely to have squamous cell carcinomas of the head and neck that are negative for exposure to humam papilloma virus. When both blacks and whites were negative for evidence of exposure to humam papilloma virus, there was no significant difference in mortality with respect to squamous cell carcinomas of the head and neck.

12 posted on 08/04/2009 12:51:23 AM PDT by neverdem (Xin loi minh oi)
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To: neverdem

So are they saying Whites are living longer because they ARE having more oral sex then Blacks?


13 posted on 08/04/2009 4:24:34 AM PDT by fortheDeclaration ("Our constitution was made only for a moral and religious people".-John Adams)
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To: fortheDeclaration
Are they saying that blacks are surviving for shorter periods then whites because they have more oral sex then whites?

no...because they are having more oral sex than blacks....

Solutions..... blacks need to have more oral sex in order to get the virus that causes the cancer... jeez, simple solution.

14 posted on 08/04/2009 5:23:23 AM PDT by erman (Outside of a dog, a book is man's best companion. Inside of a dog, it's too dark to read.)
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To: erman

As PETULA CLARK lyrics say “When you’re alone and life is making you lonely. You can always go - downtown.”


15 posted on 08/04/2009 6:01:46 AM PDT by Colorado Cowgirl (God bless America!)
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To: grey_whiskers

It might help the Town Hall meeting to talk about how the Great Society created an entire class of people that have problems caused by government - no men in a welfar home, no work, high % in jail - then ask “Is the great society program of the LBJ error a road map for health care?”


16 posted on 08/04/2009 6:21:55 AM PDT by q_an_a
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To: erman
Solutions..... blacks need to have more oral sex in order to get the virus that causes the cancer... jeez, simple solution.

Why would they want the virus that causes the cancer?

How did the get the cancer if they didn't have the virus in the first place?

17 posted on 08/05/2009 2:51:34 AM PDT by fortheDeclaration ("Our constitution was made only for a moral and religious people".-John Adams)
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To: fortheDeclaration

It’s insanity. They are saying that whites with head/neck cancer are surviving longer because their cancers are more often caused by HPV, which doesn’t kill you as quick apparently. Then they take the rationale further by saying the whites are getting cancer from HPV more often because of differing sexual behavior than blacks. But they are leaving out so much- if let’s say whites get cancer from HPV more often than blacks because they have more oral sex which apparently makes it easier to spread the HPV virus, then it should also follow that whites are getting cancer more often, there being this additional risky behavior. So what’s being touted as “better”; longer survival based on cause of the cancer; carries with it the implication there are more whites percentage getting head/neck cancers. So how can surviving longer but more people getting cancer, be better than less people getting cancer even if those people don’t survive as long. Seeing as the longer survival time is still less than two years you are dying pretty quick either way.


18 posted on 08/05/2009 3:29:04 AM PDT by visualops (portraits.artlife.us or visit my freeper page)
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To: visualops
Thank you! I knew it didn't make sense.

That is why they tried to make it so hard to understand!

Another great 'research study'!

19 posted on 08/05/2009 3:31:26 AM PDT by fortheDeclaration ("Our constitution was made only for a moral and religious people".-John Adams)
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To: fortheDeclaration
How did the get the cancer if they didn't have the virus in the first place?

smoking , drinking alcohol, mouthwash with alcohol, diet lacking in beta carotene, low intake of vitamin C, poor dental hygiene ......

20 posted on 08/05/2009 4:29:14 AM PDT by erman (Outside of a dog, a book is man's best companion. Inside of a dog, it's too dark to read.)
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