That Dan Wesson is a mighty pretty gun. How does your Sig 220 perform? I have both the Glock 21 and the H and K USP in .45 auto. They both work well, but they are totally different ergonomically. (Is that a real word?)
I do not have a USP .45 but my P2000 ergos are very nice, however, the trigger is crap compared to a Sig.
I've been shooting P226STs in 9 for years but I actually shoot my new P220ST better.
You owe it to yourself to try a steel gun.
Here's my little Sig collection: