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Doctors test ways to grow knee cartilage (adult stem cells)
Seattle Post Intelligencer ^ | 8/21/2006 | LAURAN NEERGAARD

Posted on 08/21/2006 6:53:19 PM PDT by markomalley

WASHINGTON -- Doctors are testing new ways to spur cartilage to regrow in damaged knees, from implanted "cartilage plugs" to injections of bone-marrow stem cells.

The need is huge. Knees are the joint most likely to go bad, and the cartilage that cushions them has only a limited natural ability to repair itself.

The question is how to unlock that ability and give it a boost.

The potential new options are being tried first in people who injured their knees and thus need small amounts of cartilage to regrow. But if they truly work, the techniques one day might offer hope for arthritis sufferers, too, whose cartilage over time completely erodes.

Most eagerly anticipated: the first clinical trial using stem cells from donated bone marrow to try to regenerate the knee's shock absorber, a cartilage pad called the meniscus.

Meniscus injuries are common, and not just among young athletes. Because the pad weakens with age, a simple wrong step can leave an older person with the painful tear. About 800,000 Americans a year have part of the meniscus surgically removed, to relieve pain when jagged edges won't heal.

Stem cells are building blocks for tissue. Mesenchymal stem cells are a type of adult stem cell that live in the bone marrow and can transform into cartilage-forming cells called chondrocytes. Mixing these stem cells with a knee-lubricating fluid helped the meniscus regrow in goats. Will it work in people?

Researchers enrolled 55 patients who had about half their meniscus removed. About a week after that surgery, each participant received a single injection - either a dummy shot or one containing millions of mesenchymal stem cells.

(Excerpt) Read more at seattlepi.nwsource.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: adultstemcells
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Mesenchymal stem cells are a type of adult stem cell that live in the bone marrow and can transform into cartilage-forming cells called chondrocytes. Mixing these stem cells with a knee-lubricating fluid helped the meniscus regrow in goats.

Still yet, once again, good results for the use of adult stem cells (vice nothing--???-- for embryonic ones)

When will they get the message???

1 posted on 08/21/2006 6:53:21 PM PDT by markomalley
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To: Coleus; Pyro7480; cpforlife.org; Salvation

pro-life, adult stem cell ping??


2 posted on 08/21/2006 6:54:44 PM PDT by markomalley (Vivat Iesus!)
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To: markomalley

This is good news indeed.

I could use some new joints......the original equipment is getting a bit worn and painful....


3 posted on 08/21/2006 6:58:32 PM PDT by Conservative Goddess (Politiae legibus, non leges politiis, adaptandae)
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To: markomalley
This is amazing.About 18 months ago,I was diagnosed as having substantial damage to the cushioning lining of one of my hip sockets.It's raised havoc with my ability to walk easily.

I just might call my orthopedic surgeon and ask if there are any research studies underway in Boston,New Haven,NYC,etc using adult stem cells.

4 posted on 08/21/2006 7:00:43 PM PDT by Gay State Conservative ("An empty limousine pulled up and Hillary Clinton got out")
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To: markomalley

This is great news! I really need cartilage in both of my knees.


5 posted on 08/21/2006 7:01:45 PM PDT by Solson (magnae clunes mihi placent, nec possum de hac re mentiri.)
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To: markomalley

I want to volunteer!


6 posted on 08/21/2006 7:03:53 PM PDT by Exit148 (Founder of the Loose Change Club. Every nickle and dime counts!!)
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To: Mrs. Don-o

ping


7 posted on 08/21/2006 7:05:34 PM PDT by don-o (Proudly posting without reading the thread since 1998. (stolen from one cool dude))
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To: markomalley

This is incredible. I'm only in my late 20's, but a decade of hard sports has left me aching in the knees everyday.


8 posted on 08/21/2006 7:07:58 PM PDT by JerseyHighlander
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To: markomalley

its like new snake oil


9 posted on 08/21/2006 7:09:12 PM PDT by Flavius (Qui desiderat pacem, praeparet bellum)
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To: markomalley

Certain segments of society don't want to hear anything about adult stem cells. They're in hot pursuit of another profit center for Planned Parenthood.


10 posted on 08/21/2006 7:09:34 PM PDT by RegulatorCountry
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To: markomalley

Two new disks for my back, please. Are they made of cartilage?


11 posted on 08/21/2006 7:10:12 PM PDT by LibWhacker (There are no such things as moderate muslims, only jihadis in a larval stage.)
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To: markomalley; 2ndMostConservativeBrdMember; afraidfortherepublic; Alas; al_c; american colleen; ...


12 posted on 08/21/2006 7:12:17 PM PDT by Coleus (God hates moderates, Revelation 3:15-16)
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To: Gay State Conservative
DO THAT! Enrolling as a subject in clinical studies happens all over the place, you get PAID for it, and you get cutting-edge care.

My friend does the studies, and I work for a biotech.

13 posted on 08/21/2006 7:31:02 PM PDT by gaijin
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To: Conservative Goddess

I'll take one good joint!!!!


14 posted on 08/21/2006 7:35:06 PM PDT by CGASMIA68
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To: Solson

My Doc said I wont need a knee replacement because within 10 yts we'll be able to take a pill that grows cartilage. Hopefully this is it.


15 posted on 08/21/2006 7:35:22 PM PDT by hubbubhubbub
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To: t1b8zs

LOL......


16 posted on 08/21/2006 7:36:20 PM PDT by Conservative Goddess (Politiae legibus, non leges politiis, adaptandae)
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To: markomalley
We're already injecting injured tendons of horses with stem cells and the tendons in horses are healing amazingly. For almost 20 years, veterinarians have been touting glucosamine as a nutritional supplement that augments the healing of joints and human orthopods have resisted the data until just recently. Medicine is undergoing logrithmic advances that are hard for one to keep up with efficiently.
17 posted on 08/21/2006 7:37:29 PM PDT by vetvetdoug
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To: gaijin

"I work for a biotech."

I had to do a double-take, because I missed the "e." Biotech is much better, lol.


18 posted on 08/21/2006 7:48:22 PM PDT by RegulatorCountry
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To: All

Wish insurance would cover these kinds of treatments.


19 posted on 08/21/2006 8:07:35 PM PDT by Sun (Hillary had a D-/F rating on immigration; now she wants to build a wall????)
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To: hubbubhubbub

"My Doc said I wont need a knee replacement because within 10 yts we'll be able to take a pill that grows cartilage."

That would be great!


20 posted on 08/21/2006 8:09:06 PM PDT by Sun (Hillary had a D-/F rating on immigration; now she wants to build a wall????)
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