This is an XB-70 with an X15. I have always thought the XB-70 looked like something to base a concept like this on.
The B-52 was also studied as a launch platform for the X-20:
Regardless of whether or not this hypothetical TSTO was actually built, the basic idea continues, such as the Andrews Space "Peregrine" aircraft-based launch system:
And the X-42 demonstrator, capable of lobbing either a military CAV, or as a reusable first stage for smallsat launch:
The XB-70 was too good a plane to entirely disappear, and it didnt, it just went black.