RINOs have and will always be the poison pill within the Republican Party, essentially operatives from the Democrat Party to turn the GOP into Democrat-lite, screwing everything up they can, our civil liberties and Constitutional rights be damned.
And conservatives aren't partiless unless they choose to be. There's always the Constitutional Party. If that mvoe allows the Dems to win an election or two, well, it may just be the wake-up call the GOP, and the country, needs.